The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting.
By Miriam Merad, P. Sathe, J. Helft, Jennifer Miller, A. Mortha. Annual Review of Immunology, 2013
2,206 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/78d5cdeb5a036c64d14ba91ab6df95938c34e5c7
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In Immunology
- A. Mildner
- Steffen Jung
- C. Varol
- Florent Ginhoux
- Miriam Merad
- R. Medzhitov
- B. Ruffell
- C. Reis e Sousa
Citations in the corpus
- Exosome-Based Cell-Cell Communication in the Tumor Microenvironment (2018, background): “Dendritic cells (DCs) are versatile meditators of the immune system, forming a remarkable network that shapes innate and adaptive immunity, according to peripheral signals (Merad et al., 2013).”
- Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy (2019, background): “We identified two clusters of conventional DCs, including CD1c+/DC2 (expressing CD1C, CD1D, CLEC10A, FCER1A, FCGR2B) and CD141+/DC1 (expressing BATF3, CLEC9A, XCR1, CADM1, CLNK, C1orf54) (Figure 2C), consistent with high-resolution single-cell analyses in recent studies (Guilliams et al., 2016; See ”
- The spleen in local and systemic regulation of immunity (2013, background): “Splenic DCs originate from bone marrow HSCs, specialize in antigen processing and presentation, and are key initiators and controllers of adaptive immunity (Merad et al., 2013).”
- Tolerogenic dendritic cells (2016, background): “Two major classes of DCs have been identified based on their morphological and functional features: classical DCs (cDCs) and plasmacytoid DCs (pDCs). cDCs are also classified in two types based on the expression of CD8 and CD11b.”
- OMIP-044: 28-color immunophenotyping of the human dendritic cell compartment (2018, background): “While adaptive immune cells such as T and B lymphocytes are widely studied as the essential effector cells of the immune system, APCs are the upstream gatekeepers initiating and shaping virtually any adaptive immune response (1,2).”
- Macrophages: development and tissue specialization. (2015, methodology): “It is, however, now firmly established that classical DCs rely on dedicated precursors for their maintenance (12) and that most tissue macrophages are of embryonic origin and are independent of monocyte input (14, 44).”