Two-component signal transduction

By R. Bourret, R. Silversmith. Current Opinion in Microbiology, 2010

1,404 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1eb56435c84ee3172a7ce58c01431a3769a9e13a

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Citations in the corpus

Biological Insights from Structures of Two-Component Proteins (2009, background): “Emphasis is placed on recent advances rather than historical studies that laid the foundation of the field and have been reviewed previously (37, 47, 87).”
Cytokinin signaling in plant development (2018, background): “…transduction The cytokinin signal transduction pathway involves a His-Asp phosphorelay similar to that found in bacterial two-component signaling systems, which are the major routes by which bacteria sense and respond to environmental stimuli (Cheung and Hendrickson, 2010; Stock et al., 2000).”
Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information (2014, background): “An example of such a case is the interfacial T82 residue located on the β 4 − α 4 loop that is found to be present in 73% of RR receiver domains in our cognate pair alignment and has been implicated as being one of the catalytically important residues in RR proteins (1, 46).”
Genes and Molecules of Lactobacilli Supporting Probiotic Action (2008, background): “then transferred to the regulatory domain of the response regulator (RR), which in turn induces a transcriptional response through its DNA-binding domain (237).”
Simultaneous identification of specifically interacting paralogs and interprotein contacts by direct coupling analysis (2016, background): “They consist of two interacting proteins, the Histidine sensor kinase (SK), as a signal receiver, and the response regulator (RR), which, under activation, typically acts as a transcription factor and triggers a transcriptional response (30).”
Bacterial Quorum-Sensing Network Architectures (2009, neutral): “A typical two-component system consists of a membrane-bound histidine kinase receptor and a cognate cytoplasmic response regulator, which functions as a transcriptional regulator (39, 41, 109).”
Microbial Surface Colonization and Biofilm Development in Marine Environments (2015, background): “The biological pump provides one of the biological mechanisms contributing to the oceanic sink of atmospheric CO2 via the settlement of biogenic organic particles out of the ocean surface waters. microbial carbon pump The process of microbial transformation of labile dissolved organic carbon to reca”
Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. (2013, background): “It is also possible for multiple SKs to phosphorylate the same RR or for a single SK to phosphorylate several RRs, as is the case for chemotaxis, in which a single SK, CheA, phosphorylates two RRs, CheB and CheY (Li et al., 1995), or in the quorum-sensing cascade of Vibrio harveyi where the SKs LuxN”
A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis (2012, neutral): “The two component system is the most prevalent form of signal transduction enabling bacteria to alter cellular behavior in response to environmental cues (Stock et al., 2000).”
Bacterial quorum sensing: its role in virulence and possibilities for its control. (2012, background): “Extracellular AIPs are detected via membrane-bound two-component sensor kinases (Hoch and Silhavy 1995; Inouye and Dutta 2003; Simon et al. 2007).”
Connecting the Sequence-Space of Bacterial Signaling Proteins to Phenotypes Using Coevolutionary Landscapes (2016, background): “An important example is two-component signaling (TCS) (Hoch 2000; Stock et al. 2000; Laub and Goulian 2007; Casino et al. 2010; Szurmant and Hoch 2010; Capra and Laub 2012), which serves as the primary means for bacteria to sense the environment and carry out appropriate responses.”
Rewiring the specificity of two-component signal transduction systems. (2008, neutral): “In bacteria, the predominant family of signaling proteins is the two-component signal transduction system (Stock et al., 2000).”
Accurate prediction of protein–protein interactions from sequence alignments using a Bayesian method (2008, background): “The matrix components R ij and ˜ R ij correspond to the ratios of probabilities of all observed data in columns ( i, j ) under a general dependent model and under the assumption that i and j are independent.”
PathogenFinder - Distinguishing Friend from Foe Using Bacterial Whole Genome Sequence Data (2013, background): “Among the molecular features that a bacterium needs to infect and survive inside its host [9] are exotoxins, endotoxins, two components systems [10], adherence factors, secretion systems (I to IV type) [11], through which bacteria can inject their toxins into its hosts cells [12].”
Salmonella enterica Serovar Typhimurium Skills To Succeed in the Host: Virulence and Regulation (2013, background): “These regulators also contain an effector domain, which is often a DNA binding moiety activated upon phosphorylation to eventually alter gene transcription (250, 251).”
Fundamental Limits to Cellular Sensing (2015, background): “And many cellular signaling pathways, including two-component systems in bacteria [74], GTP-ase cycles as in the Ras system [63], phosphorylation cycles as in MAPK cascades [19], are driven out of thermal equilibrium via the turnover of fuel.”