Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases.

By M. Bibikova, Mary M. Golic, K. Golic, D. Carroll. Genetics, 2002

848 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1dc07aac70ddcbcae81dcbd3f9c92c5adb6f7519

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Citations in the corpus

Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing? (2019, methodology): “Genome editing using targetable nucleases such as ZFNs (Bibikova et al., 2002; Doyon et al., 2008; Geurts et al., 2009; Urnov et al., 2010), TALENs (Huang et al., 2011; Tesson et al., 2011; Joung and Sander, 2013) and CRISPR/Cas9 (Cong et al., 2013; Jinek et al., 2013; Mali et al., 2013a; Hwang et a”
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases (2008, unknown): “Targeting a double-strand break to a specific site in the genome with ZFNs has been used to disrupt permanently the genomic sequence surrounding the ZFN target site in a variety of eukaryotic organism”
The new frontier of genome engineering with CRISPR-Cas9 (2014, unknown): “When designed to recognize a chromosomal sequence, such zinc finger nucleases (ZFNs) were found to be effective at inducing genomic sequence changes in Drosophila and mammalian cells (29, 30).”
TALENs: a widely applicable technology for targeted genome editing (2012, unknown): “ZFNs have been used to introduce NHEJ-or HDR-mediated gene alterations in fruit fly 33, 34 , roundworm 7, 35 , zebrafish 36, 37 , rainbow trout 38 , catfish 39 , sea urchin 40 , frog 41 , pig 42 , cattle 43 , cricket 8 , rabbit 44 , silkworm 45 , butterfly 46 , mouse 47, 48 , rat 49, 50 , soybean…”
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling (2014, background): “for Genome Editing and Cancer Modeling Randall J. Platt,1,2,3,4,14 Sidi Chen,5,6,14 Yang Zhou,2,3 Michael J. Yim,1,2,3,4 Lukasz Swiech,1,2,3,4 Hannah R. Kempton,1,2,4 James E. Dahlman,5,7,8 Oren Parnas,1 Thomas M. Eisenhaure,1,11 Marko Jovanovic,1 Daniel B. Graham,1 Siddharth Jhunjhunwala,5 Matthias”
Heritable Targeted Gene Disruption in Zebrafish Using Designed Zinc Finger Nucleases (2008, background): “NHEJ-based repair of a ZFN-induced DSB has been exploited to disrupt a gene in Drosophila”
Revealing Off-Target Cleavage Specificities of Zinc Finger Nucleases by In Vitro Selection (2011, background): “But the toxicity of ZFNs is believed to result from DNA cleavage rather than binding alon”
Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System (2013, background): “We tested a variety of concentrations of Cas9 mRNA:sgRNA and found the effi- ciency of NHEJ-based deletions to be concentration dependent (Table 1).”
Development and Applications of CRISPR-Cas9 for Genome Engineering (2014, unknown): “Moreover, it was shown in the absence of an exogenous homology repair template that localized DSBs can induce insertions or deletion mutations (indels) via the error-prone nonhomologous end-joining (NHEJ) repair pathway (Figure 2A) (Bibikova et al., 2002).”