Human and avian influenza viruses target different cell types in cultures of human airway epithelium.

By M. Matrosovich, T. Matrosovich, T. Gray, N. Roberts, H. Klenk. Proceedings of the National Academy of Sciences of the United States of America, 2004

806 citations recorded by the source corpus.

Subfields: Agronomy and Crop Science, Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/1d88e3d1a44eb6220e525cbb9a0602cee598251e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Agronomy and Crop Science

1. E. De Clercq

In Epidemiology

1. P. Palese
2. Yoshihiro Kawaoka
3. E. De Clercq

In Infectious Diseases

1. S. Weiss
2. Kwok-Yung Yuen
3. P. Palese
4. J. Leibowitz

Citations in the corpus

• Influenza: lessons from past pandemics, warnings from current incidents (2005, background): “Recently, α2,3-linked sialic acids were identified on ciliated cells in differentiated cultures of human tracheobronchial epithelium, and avian, but not human, viruses infected these cell”
• THE BIOLOGY OF INFLUENZA VIRUSES (2008, background): “Sialic acids with terminalα-2,3-linkages are also present in human respiratory epithelium, though in less abundance than those with α-2,6-linkages [19,20]; consequently, humans and other primates can be infected by avian influenza viruses, albeit with overall less efficiency than by human strains [2”
• Coronavirus Pathogenesis (2011, background): “In the case of the influenza neuraminidase, the sialic acid specificity of the enzymatic activity was shown to determine the cell subtype infected within the respiratory track and hence the pathogenic outcome (Matrosovich et al., 2004).”
• Neuraminidase Is Important for the Initiation of Influenza Virus Infection in Human Airway Epithelium (2004, background): “) at the air-liquid interface in serum-free growth factor and hormone-supplemented medium (6, 8).”
• Human Infection with an Avian H9N2 Influenza A Virus in Hong Kong in 2003 (2005, background): “Furthermore, some of the H9N2 influenza viruses currently circulating in southern China have molecular features that allow them to preferentially bind to -2,6-NeuAcGal receptors (1, 14, 18, 19).”