Neuraminidase Is Important for the Initiation of Influenza Virus Infection in Human Airway Epithelium

By M. Matrosovich, T. Matrosovich, T. Gray, N. Roberts, H. Klenk. Journal of Virology, 2004

617 citations recorded by the source corpus.

Subfields: Epidemiology

View Paper: https://www.semanticscholar.org/paper/d664764777aeb068138ca18524d1c5e24343f584

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In Epidemiology

1. E. De Clercq
2. A. Varki
3. P. Palese

Citations in the corpus

• Antiviral agents active against influenza A viruses (2006, background): “The neuraminidase might also have a role early in influenza infection of the human airway epithelium 26 .”
• THE BIOLOGY OF INFLUENZA VIRUSES (2008, background): “The NA is also thought to aid virus infectivity by breaking down the mucins in respiratory tract secretions and allowing the virus to penetrate through to the respiratory epithelium, and it may play a role in virus entry into respiratory epithelial cells [ 48 ].”
• Biological roles of glycans (2016, background): “For example, the sialic acid binding (“hemagglutinating”, H) activity of the influenza viruses is balanced by the activity of its sialic acid releasing enzyme (neuraminidase, N), the latter working both to allow the virus to gain access to cell surfaces by cutting through interfering molecules (788,”