The DEAD-box protein family of RNA helicases.

986 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The many pathways of RNA degradation. (2009, background): “Alternatively they might act as ‘‘place markers’’ remaining temporarily fixed in position while signaling to, or directly recruiting, the degradation machinery (reviewed in Cordin et al., 2006; Rajkowitsch et al., 2008).”
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense (2020, background): “DEAD-box helicases are conserved from bacteria to mammals [4].”
Establishing the role of ATP for the function of the RIG-I innate immune sensor (2015, background): “Many important ATP binding interfaces, such as the Q motif and motif VI (Cordin et al., 2004, 2006; Luo et al., 2011; Luo et al., 2012a), are not perturbed by the K270 mutation, and therefore a strong ATP binding cleft can still be formed if it is reinforced by additional interactions with short…”
From unwinding to clamping — the DEAD box RNA helicase family (2011, background): “DEAD box helicases have central and, in many cases, essential physiological roles in cellular RNA metabolis”
Pre-mRNA processing reaches back to transcription and ahead to translation. (2009, neutral): “DEAD-box proteins, a subgroup of the DExH/D-box family of RNA-dependent ATPases, are often presumed to function as RNA or RNP remodelers on the basis of their sequence similarity to the SF2 family of DNA helicases (Cordin et al., 2006; Jankowsky and Fairman, 2007).”