Structural Dynamics of Eukaryotic Chromosome Evolution

By Evan E. Eichler, D. Sankoff. Science, 2003

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Mauve: multiple alignment of conserved genomic sequence with rearrangements. (2004, background): “…whereas genome rearrangements can be readily observed between both closely related and divergent organisms of all types (Tillier and Collins 2000; Eichler and 2 similar to Smith-Waterman and Needleman-Wunsch (Thompson et al. 1994; Morgenstern et al. 1996; Morgenstern 1999; Notre-dame et al.…”
Robustness, evolvability, and neutrality (2005, background): “and small are frequent in many eukaryotes [31], such DNA elements can come to reside in the vicinity of a gene, where previously neutral mutations can affect transcription, translation,”