Heterochromatic Silencing and HP1 Localization in Drosophila Are Dependent on the RNAi Machinery
By M. Pal‐Bhadra, B. Leibovitch, Sumit G. Gandhi, Madhusudana Rao, U. Bhadra, James A. Birchler, Sarah C. R. Elgin. Science, 2004
725 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/1b52fa1ee5bdc00f5145b48ccd706e88330cbcc1
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Citations in the corpus
- Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein (2005, methodology): “= 4) was subtracted from the value determined for each YFP-expressing eye. Eye pigment was measured as described [”
- The role of RNA interference in heterochromatic silencing (2004, background): “In Drosophila , the Ago mutants aubergine and piwi disrupt TGS of transgene tandem repeats, which lose H3mK9 (ref”
- PIWI-interacting small RNAs: the vanguard of genome defence (2011, background): “Some results suggested that PIWI influences position-effect variegation in somatic cells, wherein gene silencing depends on the genomic loci, by directing Heterochromatin protein 1A (HP1A) localization to heterochromati”
- RNAi-mediated pathways in the nucleus (2005, background): “fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=31271"> white eye-colour gene or by the reversal of silencing of white transgenes that are inserted into the heavily heterochromatic fourth chromosom”
- Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. (2005, background): “Mutation of components of the RNAi pathway in Drosophila led to loss of H3mK9 methylation and delocalization of the HP proteins (Pal-Bhadra et al. 2004) as did Dicer inactivation in DT40 cells (Fukagawa et al. 2004).”
- RNA meets chromatin. (2005, background): “Homeless is required for RNA localization during embryogenesis (Gillespie and Berg 1995), and has recently been shown to be important for RNAi-dependent heterochromatin formation in flies (Pal-Bhadra et al. 2004).”