Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.
By R. Akhtar, A. B. Reddy, E. Maywood, J. Clayton, V. King, Andrew G Smith, T. Gant, M. Hastings, C. Kyriacou. Current Biology, 2002
818 citations recorded by the source corpus.
Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Physiology
View Paper: https://www.semanticscholar.org/paper/19cc7207d0ecc722043be7067860f851ac4b5307
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cognitive Neuroscience
In Endocrine and Autonomic Systems
- J. Takahashi
- Satchidananda Panda
- U. Albrecht
- C. H. Ko
- John B. Hogenesch
- C. Green
- Michael Hughes
- Steve A. Kay
In Physiology
- J. Takahashi
- Satchidananda Panda
- U. Albrecht
- John B. Hogenesch
- C. Green
- U. Schibler
- C. H. Ko
- Ethan D. Buhr
Citations in the corpus
- Rhythmic histone acetylation underlies transcription in the mammalian circadian clock (2003, background): “These slave oscillators, in turn, generate local rhythms in physiological processes that control tissue-specific function”
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks. (2010, background): “studies revealed that many genes involved in metabolism are rhythmically expressed (191, 192, 194, 199, 239, 240).”
- Harmonics of Circadian Gene Transcription in Mammals (2009, background): “Consequently, studies have been performed in several model systems to identify rhythmically expressed genes in both central and peripheral tissues [8,11–21].”
- Molecular components of the Mammalian circadian clock. (2013, background): “Between 2 and 10 % of the total genome is transcribed in a circadian manner in various mouse tissues (Kornmann et al. 2001; Akhtar et al. 2002; Panda et al. 2002a; Storch et al. 2002, 2007; Miller et al. 2007).”
- Permutation test for periodicity in short time series data (2006, neutral): “Although these values were larger than previously reported in liver [7,8,3], they may still underestimate the actual number of oscillating genes.”
- Mammalian circadian biology: elucidating genome-wide levels of temporal organization. (2004, background): “A similar proportion of cycling transcripts were found in the liver by at least four different groups (6, 144, 187, 200).”
- A clockwork web: circadian timing in brain and periphery, in health and disease (2003, background): “Mammalian clock genes are also expressed rhythmically in peripheral tissues, although sustained circadian expression is lost in SCN-lesioned animal”
- NOVEL DINOFLAGELLATE CLOCK‐RELATED GENES IDENTIFIED THROUGH MICROARRAY ANALYSIS 1 (2003, background): “The results indicate that from 2% to 8% of the genes analyzed may follow a circadian pattern (Harmer et al. 2000, Claridge-Chang et al. 2001, Grundschober et al. 2001, Schaffer et al. 2001, Akhtar et al. 2002, Duffield et al. 2002).”
- A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. (2004, methodology): “…expression analyses using high-density DNA miIntroduction croarrays to identify rhythmically expressed genes in the mouse SCN, liver, and heart (Akhtar et al., 2002; Circadian clocks provide an adaptive advantage by co- Panda et al., 2002a; Storch et al., 2002; Ueda et al., ordinating…”
- BMAL1 and CLOCK, Two Essential Components of the Circadian Clock, Are Involved in Glucose Homeostasis (2004, background): “Genes relevant to the molecular clock are also expressed in peripheral tissues (Akhtar et al. 2002; Kita et al. 2002; Panda et al. 2002; Storch et al. 2002; Oishi et al. 2003) where approximately 5%–10% of the transcriptome is subject to circadian oscillation (Albrecht and Eichele 2003).”