Type 1 T regulatory cells
By M. Roncarolo, R. Bacchetta, C. Bordignon, S. Narula, M. Levings. Immunological Reviews, 2001
906 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/17772a34f52f41f274311efedc9b8179745b551a
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In Immunology
Citations in the corpus
- Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype (2003, background): “Such cells suppress immune responses through either direct cell–cell interactions or the release of inhibitory cytokines such as IL-10 and transforming growth factor-β (TGF-β”
- Cancer immunotherapy via dendritic cells (2012, positive): “Thus, T Reg cells can inhibit CTLs through the secretion of IL-10 (Ref”
- Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells1 (2004, methodology): “Our data suggest that Tr1/Th3-like T cells (22, 23) secreting both IL-10 and TGF- could be detected in melanoma metastatic LNs among CD4 CD25 T cells.”
- Tolerogenic dendritic cells (2016, background): “Both in mice and humans, IL-10 and IL-27 are linked to the induction of CD4 T cells with regulatory function [7, 9, 10].”
- Regulatory T cells in transplantation tolerance. (2005, background): “One type, characterized through its singular secretion of the cytokine IL-10, has been loosely referred to as a Tr1 cell (Groux et al. 1997; Roncarolo et al. 2003).”
- Interleukin-10 Therapy—Review of a New Approach (2003, background): “Additionally, IL-10 supports the generation of regulatory T cells (Levings et al., 2001a; Roncarolo et al., 2001).”
- Regulatory T cells and mechanisms of immune system control (2004, background): “More recently, T reg cells producing IL-10 (IL-10 T reg ) and secreting transforming growth factor (TGF)-β were describe”