Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

By E. Ng, W. W. S. Chong, H. Jin, E. Lam, V. Shin, J. Yu, T. Poon, S. Ng, J. J. Sung. Gut, 2009

1,139 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/15a67d600997dca125b7ece2650d39c7005f4868

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In Cancer Research

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Citations in the corpus

Circulating microRNAs in plasma of patients with gastric cancers (2010, background): “In fact, accumulating reports also suggest the potential of miRNAs in the early detection of patients with several malignancies, such as lymphoma, colorectal cancer, tongue cancer and ovarian cancer (Lawrie et al, 2008; Wong et al, 2008; Ng et al, 2009; Resnick et al, 2009).”
Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies (2011, background): “themiRNAbiomarkerswe examined,weobserved variation attributable to blood cell effects that was greater in magnitude thanmanyof the differences reported betweenpatients with cancer and controls (13, 15, 20).”
Circulating Exosomal microRNAs as Biomarkers of Colon Cancer (2014, background): “Several reports have suggested the use of circulating miRNAs in whole plasma or serum, including miR-141, miR-21, miR-221, miR-29, and miR92a, as diagnostic biomarkers of CRC [26–30].”
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction (2010, background): “Further, miR-133a has been found to increase in the bloodstream of patients with lung cancer(29) and with colorectal cancer.(30) In contrast, a decrease in circulating miR-122 and -375 has not been reported in any other medical condition examined to date, neither in humans nor in the animal models o”
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma (2011, methodology): “By using quantitative RT-PCR (qRT-PCR), we assayed the vesicle pellets and the vesicle-poor supernatants for three well characterized circulating miRNAs: miR-16, miR-92a, and let-7a (1, 8, 24).”
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease (2013, positive): “Another study that comprised 90 patients with CRC, 90 patients with inflammatory bowel diseases (IBD), 20 patients with gastric cancer and 50 healthy controls also confirmed high expression level of miR-17 and miR-92 in tumors and serum from patients with CRC.(63) Patients with CRC had higher miR92 ”
Cell-free nucleic acids as biomarkers in cancer patients (2011, background): “miRNA expression profiles have since been shown to have signatures that are related to tumour classification, diagnosis and disease progressio”
Circulating MicroRNAs as a Novel Class of Diagnostic Biomarkers in Gastrointestinal Tumors Detection: A Meta-Analysis Based on 42 Articles (2014, background): “Subsequently, miRNAs as molecular markers have attracted much attention in cancer diagnosis [20,21,44,54,67].”
Secreted monocytic miR-150 enhances targeted endothelial cell migration. (2010, background): “, 2008), a large number of studies have also reported that circulating miRNAs can serve as biomarkers for various diseases (Resnick et al., 2009; Ng et al., 2009; Wang et al., 2009).”