The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

By Xuan Zhang, Dongya Zhang, Huijue Jia, Q. Feng, Donghui Wang, Di Liang, Xiang-ni Wu, Junhua Li, Longqing Tang, Yin Li and 38 more. Nature Medicine, 2015

1,542 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/1408df3cee417736f65f092e7f4399bffaac5233

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Curtis Huttenhower
2. K. Takeda
3. Shimon Sakaguchi
4. Henry J. Haiser
5. Ramnik J. Xavier
6. Nicola Segata
7. D. Zheng
8. Eran Elinav

In Molecular Biology

1. Nicola Segata
2. Curtis Huttenhower
3. Eric A. Franzosa
4. Edoardo Pasolli
5. Adrian Tett
6. Duy Tin Truong
7. Ramnik J. Xavier
8. S. Lynch

In Rheumatology

1. M. Narazaki

Citations in the corpus

• Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation. (2017, background): “, 2016), and rheumatoid arthritis (Zhang et al., 2015).”
• Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine (2016, background): “The dysbiotic condition was partially resolved when RA disease improved upon treatment (14).”
• Interaction between microbiota and immunity in health and disease (2020, background): “in intestinal, dental and saliva specimens.(172) Microbiome-derived metabolites, most notably SCFAs, interact with a variety of immune pathways implicated in RA.”
• An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis (2016, result): “(XLSX 36 kb) Abbreviations BMI: body mass index; CII: type II collagen; DC: dendritic cell; FDR: first-degree relative; FITC: fluorescein isothiocyanate; HC: healthy control; IL: interleukin; KEGG: Kyoto Encyclopedia of Genes and Genomes; LDA: linear discriminant analysis; MTX: methotrexate; OTU: op”
• The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases (2017, neutral): “(22) Pseudomonas sp.(41) Micrococcaceae(53) Porphyromonadaceae Pseudomonas sp.”
• Gut microbiota dysbiosis contributes to the development of hypertension (2017, background): “These metabolic functions are essential for the host and have been observed in healthy populations [4, 5, 39, 40].”
• Microbial strain-level population structure and genetic diversity from metagenomes (2017, positive): “(Koren et al. 2013) and has been strongly associated with the onset of rheumatoid arthritis (Scher et al. 2013; Zhang et al. 2015).”