Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis.

By S. Justice, C. Hung, Julie A. Theriot, D. Fletcher, Gregory G. Anderson, Matthew Footer, S. Hultgren. Proceedings of the National Academy of Sciences of the United States of America, 2004

660 citations recorded by the source corpus.

Subfields: Epidemiology, Surgery, Urology

View Paper: https://www.semanticscholar.org/paper/138f168288efa8cd87b619d0a5f53a741e055317

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. B. B. Finlay
2. K. Young
3. H. Mobley
4. S. Hultgren

In Surgery

1. B. B. Finlay
2. R. Gallo

In Urology

1. K. Young
2. B. B. Finlay

Citations in the corpus

• The Selective Value of Bacterial Shape (2006, background): “These latter forms resist phagocytosis by polymorphonuclear leukocytes and thus promote infection, and the eruption of filaments from a previously infected host cell permits bacteria to infect neighboring epithelial cells (153).”
• The biology and future prospects of antivirulence therapies (2008, background): “and initiate a pathogenic cascade that involves several distinct phases as examined in the mouse cystitis mode”
• Molecular mechanisms of Escherichia coli pathogenicity (2012, background): “UPEC can leave the IBCs through a fluxing mechanism; motile UPEC leaves the epithelial cells and enters the lumen of the bladde”
• Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era (2013, background): “Although internalized UPEC are expelled in a TLR-4-dependent process (Bishop et al. 2007), some bacteria avoid the exocytic process and escape into the host-cell cytoplasm, where they replicate into IBCs (Anderson et al. 2003; Justice et al. 2004).”
• Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis (2008, background): “It is postulated that IBCs and biofilms contribute to the persistence of these organisms due to the increase in resistance to antibiotics and the host immune response.”
• The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection (2006, methodology): “We analyzed the number of bacteria that attached to urinary bladders 1 h after infection, when no influx of leukocytes into the urinary tract occur”
• Involvement of Nitric Oxide in Biofilm Dispersal of Pseudomonas aeruginosa (2006, background): “Previous studies have suggested that dispersal of single organisms from biofilms is linked to the motility of a subpopulation of cells (32, 48, 53).”
• Bacterial Biofilm and its Role in the Pathogenesis of Disease (2020, background): “bladder were consumed by neutrophils whereas bacteria that had invaded the epithelial cells were protected from neutrophil attack and could proliferate in the IBC [221].”