The biology and future prospects of antivirulence therapies
By L. Cegelski, G. Marshall, G. Eldridge, S. Hultgren. Nature Reviews Microbiology, 2008
788 citations recorded by the source corpus.
Subfields: Ecology, Molecular Biology, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/862d6a5ede5a2fb3141e37933e56ab67ae6cdb44
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In Ecology
In Molecular Biology
- David A. Rasko
- Jin-Hyung Lee
- Gautam Dantas
- Maria Kostakioti
- Jintae Lee
- M. Hadjifrangiskou
- S. Hultgren
- V. Sperandio
In Molecular Medicine
Citations in the corpus
- Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era (2013, background): “…by interfering with bacterial signaling cascades, given that two-component systems constitute a central means of intercepting and translating environmental changes (Lyon et al. 2000; Okada et al. 2007; Cegelski et al. 2008; Rasko et al. 2008; Watanabe et al. 2008; Njoroge and Sperandio 2009).”
- Indole as an intercellular signal in microbial communities. (2010, background): “, 2009a) could potentially be used for antivirulence therapies (Lesic et al., 2007; Cegelski et al., 2008), which are also known as antipathogenic drugs (Rasmussen & Givskov, 2006).”
- Anti-virulence strategies to combat bacteria-mediated disease (2010, background): “In addition, these anti-virulence drugs could potentially be used in combination with established or novel antimicrobials in a synergistic manner to extend the lifespan of these drug”
- Antimicrobial Resistance and Virulence: a Successful or Deleterious Association in the Bacterial World? (2013, background): “This approach would therefore lead to preservation of susceptible nonpathogenic bacteria, which would act as a barrier for colonization by virulent populations; antibiotic pressure would also be lowered, thus minimizing the risk for horizontal spread of drug resistance genes (430, 431).”
- The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation (2016, background): “A more complete discussion of antivirulence therapeutics can be found elsewhere [93–96].”