Involvement of Nitric Oxide in Biofilm Dispersal of Pseudomonas aeruginosa

By N. Barraud, D. Hassett, S. Hwang, S. Rice, S. Kjelleberg, J. Webb. Journal of Bacteriology, 2006

738 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/cab4ad2745491216d4f46541fe3c7b9ef8f6728d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. J. Kaplan
2. P. Watnick
3. E. Karatan
4. A. Horswill
5. Peter D. Steinberg
6. C. Beloin
7. J. Ghigo
8. D. Lebeaux

In Molecular Biology

1. J. Kaplan
2. A. Horswill
3. P. Watnick
4. E. Karatan
5. Peter D. Steinberg
6. Blaise R. Boles
7. S. Medinets
8. K. Butterbach‐Bahl

Citations in the corpus

• Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, background): “Moreover, a nirS mutant (a nitrite reductase mutant), which is unable to produce NO, forms biofilms that fail to disperse, whereas a norCB (NO reductase) mutant, which produces large amounts of NO, shows enhanced biofilm dispersal (18).”
• Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal (2011, background): “In the dispersal cells, genes that regulate features of the sessile biofilm phenotype, such as exopolysaccharides and fimbriae, are downregulated, whereas genes that encode factors which are important for a motile lifestyle, including flagella and proteins involved in chemotaxis , are upregulate”
• Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, background): “aeruginosa biofilms through induction of phosphodiesterases and, ultimately, a reduction in c-di-GMP levels (352, 353).”
• Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses (2010, background): “The NO donor sodium nitroprusside, for example, induces detachment of pre-formed P. aeruginosa biofilm colonies in vitro and greatly enhances the efficacy of antibiotics in the removal of the biofilms (Barraud et al., 2006).”
• A review of soil NO transformation: associated processes and possible physiological significance on organisms (2015, background): “A role of NO for 1292 biofilm dispersion was reported for the pathogens Pseudomonas aeruginosa 1293 (Barraud et al., 2006, 2009a) and S. aureus (Schlag et al., 2007), the 1294 myxomycete Candida albicans, as well as in mixed-species biofilms 1295 (Barraud et al., 2009b).”
• Graphene oxide: a nonspecific enhancer of cellular growth. (2011, background): “The rod-shape voids observed may be due to the process of bacteria dispersal, a process in which bacteria evacuate the interior of biofilms due to competition or lack of nutrients, leaving behind hollow, shell-like structures.(16)”
• Alternative Antimicrobial Approach: Nano-Antimicrobial Materials (2015, background): “NO NM are also effective in biofilm eradication of multiple bacterial species [107–109].”
• agr-Mediated Dispersal of Staphylococcus aureus Biofilms (2008, background): “The majority of studies on biofilm detachment have focused on factors capable of initiating the process, such as nutrient availability [54,55], nitric oxide exposure [56], oxygen tension [57], iron salts [58], chelators [59], and signaling molecules [60– 63].”