Neurobiology: Inhibitor of neurite outgrowth in humans

By R. Prinjha, S. Moore, M. Vinson, Sian Blake, R. Morrow, G. Christie, D. Michalovich, D. Simmons, F. Walsh. Nature, 2000

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Glial inhibition of CNS axon regeneration (2006, background): “Subsequent identification of the putative antigen led to the discovery of Nogo”
Neural tissue engineering: strategies for repair and regeneration. (2003, background): “NI-35, also called Nogo, was found to contain two inhibitory domains, Nogo-A (7, 257) and Nogo-66 (258).”
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. (2002, neutral): “On the other hand, because the NgR to inhibit neurite outgrowth (Chen et al., 2000; Fournier is a GPI-linked protein without a transmembrane doet al., 2001; Prinjha et al., 2000).”
Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration (2001, background): “and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injur”
Nogo-66 receptor antagonist peptide promotes axonal regeneration (2002, background): “A second domain of Nogo-A, Amino-Nogo, seems to inhibit outgrowth by a mechanism independent of Ng”
Rho Kinase Inhibition Enhances Axonal Regeneration in the Injured CNS (2003, background): “…glycoprotein (MAG) (McKerracher et al., 1994; Mukhopadhyay et al., 1994; Liu et al., 2002), chondroitin sulfate proteoglycans (Niederost et al., 1999), oligodendrocyte myelin glycoprotein (Wang et al., 2002), and Nogo (Chen et al., 2000; GrandPre et al., 2000; Prinjha et al., 2000).”