Nogo-66 receptor antagonist peptide promotes axonal regeneration

By Tadzia Grandpré, Shuxin Li, S. Strittmatter. Nature, 2002

749 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/ce331057537828f58fe0dc492701f2eda5c715c3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. J. Silver
2. Glenn Yiu
3. Martin E. Schwab
4. Zhigang He
5. M. Sofroniew
6. B. Barres

In Developmental Neuroscience

1. J. Silver
2. Glenn Yiu
3. Martin E. Schwab
4. Zhigang He

Citations in the corpus

• Regeneration beyond the glial scar (2004, background): “Antibodies directed against the Nogo receptor administered into spinal cord lesion site”
• Nogo and axon regeneration. (2004, background): “Both soluble Fc fusion proteins of the Nogo receptor subunit NgR, which blocks Nogo, and a 40-residue fragment (‘NEP1–40’) of Nogo-66, which blocks NgR, significantly reduce the inhibitory activity of myelin [23 ,36].”
• Neural tissue engineering: strategies for repair and regeneration. (2003, background): “These include a soluble truncated form of NgR (259) and a competitive antagonist peptide that binds with high affinity to NgR (260).”
• Glial inhibition of CNS axon regeneration (2006, background): “Indeed, early experiments involving the delivery of a Nogo-66 antagonist peptide (NEP1–40”