Glial inhibition of CNS axon regeneration

By Glenn Yiu, Zhigang He. Nature Reviews Neuroscience, 2006

1,574 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e33804fd82ef13f489ba86b13141343bc2b4af58

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Gerardy-Schahn
2. H. Hildebrandt
3. J. Silver
4. M. Schwartz
5. E. Shalaby
6. A. Rolls
7. R. Schnaar
8. R. Shechter

In Developmental Neuroscience

1. R. Gerardy-Schahn
2. H. Hildebrandt
3. J. Silver
4. M. Schwartz
5. E. Shalaby
6. A. Rolls
7. R. Schnaar
8. R. Shechter

In Molecular Biology

1. R. Gerardy-Schahn
2. H. Hildebrandt
3. A. Salgado
4. M. Schwartz
5. E. Shalaby
6. R. Schnaar

Citations in the corpus

• Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms (2019, background): “Moreover, the reduced capacity of the injured spinal cord for regeneration is not solely driven by the glial scar as other factors including inflammation and damaged myelin play important inhibitory role in axon regeneration (323, 324).”
• From basics to clinical: a comprehensive review on spinal cord injury. (2014, background): “Finally, there is the onset of a chronic phase, which can occur days to years after the injury, leading to neurological impairments in both orthograde and retrograde directions, including brain regions (Cramer et al., 2005; Yiu and He, 2006).”
• Biological Activities and Application of Marine Polysaccharides (2017, background): “Chitosan is able to cross the seed teguments, probably by diffusing through microscopic ruptures caused by the imbibition [67] and to interact with embryo cells, influencing the plant cellular metabolism in the following stages of development.”
• Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration. (2014, background): “MAG is one of a suite of molecules, including those on residual myelin, that limit recovery from traumatic nervous system injury by signaling axons to halt outgrowth (258, 407, 570).”
• Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury (2011, background): “The growth-supportive phenotype of denervated Schwann cells contrasts starkly with the response of endogenous CNS glia to injury [144,145].”
• The bright side of the glial scar in CNS repair (2009, background): “We focus on the emerging beneficial aspects of the scar, as the destructive features have been extensively discussed in numerous review”
• CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. (2008, background): “Multiple models have now demonstrated that the molecular composition of the scar and the production of inhibitory molecules by astrocytes are contributing factors for regenerative failure (Busch and Silver, 2007; Fawcett, 2006; Fitch and Silver, 1997a; Fitch and Silver, 2000; Liu et al., 2006; McGra”