Increased neurogenesis in a model of electroconvulsive therapy.

By T. Madsen, A. Treschow, J. Bengzon, T. Bolwig, O. Lindvall, A. Tingström. Biological Psychiatry, 2000

788 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/0fad8c8e0e87bcca89153a1554b768a2d7bfd5e3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Developmental Neuroscience

1. R. Duman
2. Fred H. Gage
3. R. Hen
4. J. Warner-Schmidt
5. E. Nestler
6. D. Abrous
7. H. Schmidt
8. Eero Castrén

In Physiology

1. R. Malenka
2. R. Duman
3. M. Le Moal
4. R. Hen
5. Peter W. Kalivas

In Psychiatry and Mental health

1. R. Duman
2. R. Hen
3. E. Nestler
4. Eero Castrén
5. H. Schmidt

Citations in the corpus

• The current state of the neurogenic theory of depression and anxiety. (2015, background): “In 2000, three of the most effective treatments of affective disorders in humans – electroconvulsive shock [47,48], fluoxetine (the prototypic SSRI) [5], and lithium [49] – were shown to boost AHN.”
• Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment (2003, result): “…treatment increases adult proliferation and neurogenesis in the hippocampus, and the time course for this effect (ie chronic, but not acute treatment) is consistent with the time course for the therapeutic action of antidepressants (Malberg et al, 2000; Madsen et al, 2000; Manev et al, 2001).”
• Short‐term and long‐term survival of new neurons in the rat dentate gyrus (2003, background): “The seemingly rapid cell death during this 1-week period can be taken as evidence that neurons born in adulthood do not live very long (e.g. Madsen et al., 2000), but it is not known whether this high rate of cell death continues, resulting in a short lifespan for adultborn granule neurons.”
• Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment (2006, background): “These newborn cells integrate into the GCL and can be detected for at least three months after treatment cessation (Madsen et al., 2000).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “In addition, chronic administration of BDNF directly into the hippocampus causes seizure activity (Scharfman et al., 2002) and a single seizure is sufficient to increase hippocampal neurogenesis (Madsen et al., 2000).”
• Antidepressants increase neural progenitor cells in the human hippocampus (2009, background): “Dividing cells become neurons in the granule cell layer (GCL) of the DG in the adult human hippocampus where BrdU immunoreactive (-IR) cells double-label with antibodies specific to neurons (neuron-specific enolase, calbindin, and neuron-specific nuclear protein (NeuN, Eriksson et al, 1998).”
• Adult neurogenesis: from precursors to network and physiology. (2005, background): “This proliferative effect is dosedependent as a series of seizures further increases neurogenesis (331).”