Mosaic analysis with double markers in mice.

By H. Zong, J. S. Espinosa, H. Su, M. Muzumdar, Liqun Luo. 2005

564 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Molecular Biology

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In Developmental Neuroscience

In Molecular Biology

Citations in the corpus

Genetic manipulation of genes and cells in the nervous system of the fruit fly (2011, methodology): “…to image vesicle release with UAS-synaptopHluorin (Miesenböck et al., 1998; Ng et al., 2002), which undergoes an increase in fluorescence upon the pH change associated with vesicle fusion, or UAS-ANF-EMD, which is specifically released from dense-core peptidergic vesicles (Rao et al., 2001).”
In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics (2011, unknown): “To confirm our findings using a different genetic model, we employed the MADM reporter (mosaic-analysis with double markers; Figure S5A) (Zong et al., 2005).”
The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing and Mosaic Analysis (2010, unknown): “‘‘Twin-spot generator’’ (TSG), which is analogous to the MADM method in mice (Zong et al., 2005), places two chimeric fluorescent proteins on the same chromosome arm in trans.”
Comprehensive Maps of Drosophila Higher Olfactory Centers: Spatially Segregated Fruit and Pheromone Representation (2007, unknown): “Single neuron labeling can be achieved by the Golgi method, genetic methods (Young and Feng, 2004; Zong et al., 2005) or by filling neurons during single-cell recording.”
A protocol for mosaic analysis with a repressible cell marker (MARCM) in Drosophila (2006, methodology): “A conceptually analogous method called mosaic analysis with double markers (MADM) has recently been developed in mic”
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain (2009, background): “(3) XFP native fluorescence or IHC of the reporter gene shows expression of the reporter gene at the protein level throughout the brain (e.”
A global double‐fluorescent Cre reporter mouse (2007, methodology): “Our own experience with single-copy cytoplasmic EGFP demonstrated strong dendritic labeling, but weaker axonal labeling in live tissues (Zong et al., 2005).”
Genetic dissection of neural circuits. (2008, unknown): “For example, recent studies have revealed unexpected relationships between lineage and axonal projection patterns of cerebellar granule cells in the mouse (Zong et al., 2005), and birth order and physiological subtypes of cortical interneurons (Miyoshi et al.”
Mosaic Analysis with Double Markers (MADM) Reveals Tumor Cell-of-Origin in Glioma (2011, unknown): “1%–1% or much lower) (Zong et al., 2005) enables one to track mutant cells throughout the entire process of tumor-”
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Hedgehog-induced medulloblastoma (2008, unknown): “These data indicate that rRL Olig2+ progenitors give rise to a subset of GC (Figure 8A), which might contribute to functional heterogeneity (Zong et al., 2005).”
Development of neural stem cell in the adult brain. (2008, background): “For example, Mosaic Analysis with Double Markers (MADM) in mice allows simultaneous labeling and gene knockout in clones of NSCs [13].”
Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury (2013, methodology): “(2) MADM transgenic reporter mice were kindly provided by Dr. Hui Zong (Zong et al., 2005; Hippenmeyer et al., 2010) and were crossed with the mGFAP-Cre mice line 73.12 (Garcia et al., 2004), which we have previously used and extensively characterized for targeting Cremediated recombination to astro”