Odor representations in olfactory cortex: "sparse" coding, global inhibition, and oscillations.

By C. Poo, Jeffery S. Isaacson. 2009

504 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cellular and Molecular Neuroscience, Sensory Systems

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Citations in the corpus

Re-evaluating circuit mechanisms underlying pattern separation (2019, neutral): “…suggests that oscillatory synchronization of projection neurons contributes to pattern separation by adding a temporal dimension to encoding, a strategy that is also employed in the mammalian olfactory 16 processing (Friedrich and Laurent, 2001; Margrie and Schaefer, 2003; Poo and Isaacson, 2009).”
Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity (2012, unknown): “We calculated a population sparseness of 0.41 and a lifetime sparseness of 0.61 (see Experimental Procedures), somewhat lower than previously observed in aPC of anesthetized rats (Poo and Isaacson, 2009).”
Cortical feedback decorrelates olfactory bulb output in awake mice (2015, background): “Corticalbulbar Feedback Is Routed through Distinct Channels of Enhanced and Suppressed Boutons Previous work in the APC has described spatially distributed and sparse odor responses (Miura et al., 2012; Poo and Isaacson, 2009; Stettler and Axel, 2009; Zhan and Luo, 2010).”
Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex (2010, unknown): “, 2010) cortices do not contain precise maps of odors or tones, respectively, and the suspected GABAergic neurons in these areas are also more broadly tuned for those features than excitatory neurons (Poo and Isaacson, 2009; Sakata and Harris, 2009).”
Functional analysis of a higher olfactory center, the lateral horn (2012, background): “This idea has also influenced thinking about the role of inhibition in the mammalian cortex (Larimer and Strowbridge, 2008; Poo and Isaacson, 2009; Stokes and Isaacson, 2010).”
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition (2010, background): “Field oscillations occur in both gamma and beta frequency bands in the olfactory bulb (91, 111, 607, 648, 795, 1003) and the piriform cortex (111, 720, 775).”
How Inhibition Shapes Cortical Activity (2011, unknown): “Similarly, inhibition has a lag of 5–10 ms relative to excitation during beta frequency oscillations (20–40 Hz) in olfactory cortex (Figures 7C and 7D; Poo and Isaacson, 2009).”
Representations of odor in the piriform cortex. (2009, unknown): “The frequency of responsive cells we observe is in accord with a recent study that employed patch-clamp recordings to sample the odorant-evoked responses of piriform cells (Poo and Isaacson, 2009).”
Driving opposing behaviors with ensembles of piriform neurons. (2011, background): “In accord with this anatomy, electrophysiological and optical imaging studies demonstrate that individual odorants activate subpopulations of neurons distributed across the piriform without apparent spatial preference (Illig and Haberly, 2003; Poo and Isaacson, 2009; Rennaker et al., 2007; Stettler ”
Origins of Cell-Type-Specific Olfactory Processing in the Drosophila Mushroom Body Circuit. (2017, unknown): “, 2002) and the rodent piriform cortex neurons where odors are encoded sparsely (Poo and Isaacson, 2009), excitatory input is similarly followed by global inhibition found in most cells.”