Iron metabolism in pathogenic bacteria.

By C. Ratledge, L. Dover. Annual Review of Microbiology, 2000

1,543 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/08aa87427c9ae4a2ba113835430f6ad682c29336

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

In Molecular Biology

In Molecular Medicine

Citations in the corpus

Dangerous liaisons: The symbiosis of entomopathogenic nematodes and bacteria (2006, background): “TbpA interacts with a surface-exposed iron-binding lipoprotein, TbpB required for iron utilization (Ratledge and Dover, 2000).”
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron (2004, background): “During infection, bacteria acquire much of their iron from the host by synthesizing siderophores that scavenge iron and transport it into the pathoge”
Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, background): “This effect is dependent on the ferric uptake repressor Fur, a global repressor of gene transcription in iron-rich environments found in P. aeruginosa and other members of the Proteobacteria (262, 330).”
The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts (2010, background): “tribute to the virulence of both animal and plant pathogens [7].”
Siderophore-Based Iron Acquisition and Pathogen Control (2007, background): “tuberculosis and Mycobacterium leprae, however, apparently use the same genes to synthesize mycobactin derivatives called carboxymycobactins, which possess a shorter carboxyalkyl chain that renders them more hydrophilic with respect to their function as extracellular siderophores (268).”
Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. (2003, background): “Accessible iron is very scarce in many environments, particularly for bacteria in mammalian hosts (Ratledge and Dover 2000).”
Social evolution theory for microorganisms (2006, background): “For example, there is facultative variation in response to environmental conditions, such as in the amount of siderophore productio”
Review: microbial mechanisms of accessing insoluble Fe(III) as an energy source (2003, background): “They are water-soluble, low molecular weight (500–1000 Da), Fe(III)-specific ligands which are induced at low iron concentrations (Guerinot 1994; Ratledge & Dover 2000 ).”
Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria (2002, background): “plex by the outer membrane protein receptors (10, 12, 26, 90).”
Structure and function of the spleen (2005, background): “Several pathogens compete for iron in serum and tissue by secreting SIDEROPHORES , which are molecules with a high affinity for iron, and these molecules are transported back into bacteria by specific receptor”
The Social Lives of Microbes (2007, background): “Siderophores are iron-scavenging molecules produced by many species of bacteria (Ratledge & Dover 2000, West & Buckling 2003).”
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. (2002, background): “…and shape of the anomalous peak bacterial siderophores bind iron orders of magnitude more tightly than lactoferrin or transferrin, directly out-suggested that the chromophore contained a single heavy atom. competing these mammalian proteins for iron during infection (Ratledge and Dover, 2000).”