Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria

By J. H. Crosa, C. Walsh. Microbiology and Molecular Biology Reviews, 2002

779 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/cae1eb49f5a7eeff5ef9df1e90d5f53d0323520e

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In Genetics

1. Mohamed A. Marahiel
2. M. Miethke

In Molecular Biology

1. Sukhwan Yoon
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3. A. DiSpirito
4. J. Semrau
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Citations in the corpus

• Plant growth-promoting rhizobacteria (PGPR): Their potential as antagonists and biocontrol agents (2012, background): “Siderophores can be defined as small peptidic molecules containing side chains and functional groups that can provide a high-affinity set of ligands to coordinate ferric ions (Crosa and Walsh, 2002).”
• Methanotrophs and copper. (2010, background): “A gene has been discovered in M. capsulatus Bath that putatively encodes a NRPS (Ward et al., 2004) The putative NRPS has adenylation, thiolation, and acetyltransferase domains, typical of extracellular metal-binding agents (Crosa & Walsh, 2002).”
• A simple double-layered chrome azurol S agar (SD- CASA) plate assay to optimize the production of siderophores by a potential biocontrol agent Bacillus (2011, background): “Under iron-limited conditions, most prokaryotic cells, certain fungi and plants elaborate multiple low-molecularweight (often < 1000 Da), high-affinity chelating agents (although some siderophores have lower affinities), which solubilizes ferric iron in the environment and transport it into the cell”
• Nonribosomal peptides synthetases and their applications in industry (2016, neutral): “Nonmodular NRPS enzymes are found in siderophore biosynthetic pathways like EntE and VibH in enterobactin, and VibE in vibriobactin [5] or as a stand-alone peptidyl carrier protein such as BlmI from the bleomycin gene cluster [6].”
• Siderophore-Based Iron Acquisition and Pathogen Control (2007, background): “In mycobactin synthesis, however, the acylation is proposed to occur prior to the N-hydroxylation since the cyclization of the Cterminal lysine, which might be catalyzed by some kind of thioesterase or condensation domain (66), was already found in isolated didehydroxymycobactins (219).”
• Utilizing the Potential of Microorganisms for Managing Arsenic Contamination: A Feasible and Sustainable Approach (2018, background): “Siderophores are the low molecular weight high-affinity iron (Fe)-chelating ligands (stability constants 1012 to 1052) with side chains and functional groups (Crosa and Walsh, 2002).”
• Antagonistic features displayed by Plant Growth Promoting Rhizobacteria (PGPR): A Review (2017, background): “Siderophores are peptide molecules that include the functional groups along with side chains that enhance the regulation of ferric ions by forming high af inity set of ligands [30].”
• Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils (2009, neutral): “Ion channels 11 (5) 13 (7) 12 (7) ABC transporters 39 (15) 70 (15) 159 (21) Secondary porters (total) 77 (37) 101 (48) 152 (57) Major facilitators 22 (9) 27 (13) 55 (17) Amino acid-polyamineorganocation facilitators 8 (3) 17 (6) 15 (5)”