Dominant repression of target genes by chimeric repressors that include the EAR motif, a repression domain, in Arabidopsis.

By K. Hiratsu, Kyoko Matsui, T. Koyama, M. Ohme-Takagi. The Plant Journal, 2003

784 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/0856b08b76be00f8c0bd811b53c6052651ee3c2c

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Citations in the corpus

SND1, a NAC Domain Transcription Factor, Is a Key Regulator of Secondary Wall Synthesis in Fibers of Arabidopsis[W] (2006, background): “…that transcriptional factors fused with the EAR repression domain act as dominant repressors to inhibit the expression of their target genes (Hiratsu et al., 2003, 2004), and dominant repression of several redundant NACs, such as RD26, VND6, VND7, NST1, and NST2, results in loss-of-function…”
NAC Transcription Factors, NST1 and NST3, Are Key Regulators of the Formation of Secondary Walls in Woody Tissues of Arabidopsis[W][OA] (2007, methodology): “…an attempt to manipulate the formation of secondary walls, we applied our chimeric repressor gene-silencing technology (CREST), in which NST1 or NST3 fused to the EAR motif repression domain (SRDX) dominantly represses the transcription of its target genes (Hiratsu et al., 2003) (Figure 6A).”
The genetics of lignin biosynthesis: connecting genotype to phenotype. (2010, background): “domain-containing transcription factors with an EAR-motif repression domain (46) to investigate their possible functions.”
Chrysanthemum Biotechnology: Quo vadis? (2013, methodology): “Chimeric REpressor gene-Silencing Technology (CRES-T), which silences transcriptional factor genes (Hiratsu et al., 2003; Shikata and Ohme-Takagi, 2008), was used to transform chrysanthemums with the Arabidopsis TCP3 chimeric repressor, resulting in plants with fringed leaves (Narumi et al.”
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation1[OPEN] (2015, background): “Vol. 169, 2015 973 three copies of the transcriptional repressor domain SRDX (Hiratsu et al., 2003), respectively.”
The NAC Transcription Factors NST1 and NST2 of Arabidopsis Regulate Secondary Wall Thickenings and Are Required for Anther Dehiscencew⃞ (2005, methodology): “…in the anther wall and, moreover, that the chimeric NST1 and NST2 repressors dominantly suppressed the expression of genes related to secondary wall thickening in the presence of endogenous and redundant factors, as demonstrated previously (Hiratsu et al., 2003; Matsui et al., 2004, 2005).”
Arabidopsis Cys2/His2-Type Zinc-Finger Proteins Function as Transcription Repressors under Drought, Cold, and High-Salinity Stress Conditions1 (2004, background): “Recently it was shown that chimeric proteins that include the ERF-associated amphiphilic repression motif act as dominant repressors (Hiratsu et al., 2003).”
ARF7 and ARF19 Regulate Lateral Root Formation via Direct Activation of LBD/ASL Genes in Arabidopsis[W] (2007, methodology): “To generate Pro35S:LBD16-SRDX, the LBD16 coding region with a transcriptional repression domain (SRDX) was generated by PCR using a primer with the SRDX (LDLDLELRLGFA) linker sequence (Hiratsu et al., 2003).”
AREB1 Is a Transcription Activator of Novel ABRE-Dependent ABA Signaling That Enhances Drought Stress Tolerance in Arabidopsis[W][OA] (2005, methodology): “Recently, Hiratsu et al. (2003) clearly demonstrated that expression of specific target genes was suppressed dominantly by a chimeric transcription factor fused to an RD derived from the EAR motif of SUPERMAN, a TFIIIAtype zinc finger repressor, even in the presence of redundant transcription…”