Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome.

By K. Wilkinson. Seminars in Cell and Developmental Biology, 2000

609 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/07e665f057c889a152a6f71bdf186c3e07eb47df

How researchers see this paper

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In Cell Biology

1. Aaron Ciechanover
2. René Bernards
3. Sebastian M. B. Nijman
4. M. Glickman
5. B. McConnell
6. A. Dirac
7. W. Dauer
8. T. Brummelkamp

In Epidemiology

1. Aaron Ciechanover
2. René Bernards
3. Sebastian M. B. Nijman
4. M. Glickman
5. B. McConnell
6. A. Dirac
7. W. Dauer
8. T. Brummelkamp

In Molecular Biology

1. René Bernards
2. Sebastian M. B. Nijman
3. A. Dirac
4. R. Kerkhoven
5. T. Brummelkamp
6. A. D’Andrea
7. Tony T. Huang
8. Aaron Ciechanover

Citations in the corpus

• The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. (2005, background): “…poxybutane (DEB), and to a lesser extent, ionizing radia- involving numerous ubiquitin-conjugating enzymes and DUBs (Chung and Baek, 1999; D’Andrea and Pellman, 1998; Kim et al., 2003; Shackelford and Pagano, 2004;*Correspondence:alan_dandrea@dfci.harvard.edu (A.D.D.); r.bernards@ Wilkinson, 2000).”
• The Ubiquitin-Proteasome Pathway and Plant Development (2004, background): “In the case of senescence, ORE9/MAX2 presumably degrades a protein that inhibits leaf senescence (Woo et al., 2001).”
• Mammalian Krüppel-Like Factors in Health and Diseases (2010, background): “Ubiquitination is a multistep protein modification process mediated by an E1 ubiquitin-activating enzyme, an E2 ubiquitin-conjugating enzyme, and an E3 ubiquitin ligase (460).”
• Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB (2003, methodology): “This was immunoprecipated with either non-immune serum (n.i.) or Flag antibody from both untreated cells (basal) or cells treated for 20 min. with TNF-a(20 0 ) and lysates were incubated with GST-IkBa (1-72) in the presence of 32P-gATP (upper panel).”
• Parkinson's Disease Mechanisms and Models (2003, background): “The reasons for the discrepancy between thethe proteasome (reviewed by Wilkinson, 2000).”
• The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. (2002, background): “Most E2s interact with several E3s (Fig.”