Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons

By Masanori Matsuzaki, G. Ellis‐Davies, T. Nemoto, Yasushi Miyashita, M. Iino, Haruo Kasai. 2001

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Eligibility Traces and Plasticity on Behavioral Time Scales: Experimental Support of NeoHebbian Three-Factor Learning Rules (2018, methodology): “The strength of an excitatory synaptic contact can be defined by the amplitude of the postsynaptic potential which is closely related to the spine volume and the number of AMPA receptors (Matsuzaki et al., 2001).”
Structural Components of Synaptic Plasticity and Memory Consolidation. (2015, background): “This form of imaging has also revealed dynamic changes in the shapes of individual dendritic spines during the uncaging of glutamate at single spines (Matsuzaki et al. 2001; Kasai et al. 2010, 2004).”
Anatomical and physiological plasticity of dendritic spines. (2007, background): “F or p er so na l u se o nl y. receptor (AMPAR) currents in spines with bigger heads (Matsuzaki et al. 2001), which is consistent with EM studies showing a positive correlation between spine head size, PSD area, and AMPAR immunolabeling (Harris & Stevens 1989, Schikorski & Stevens 1997, Takumi et…”
Do thin spines learn to be mushroom spines that remember? (2007, background): “Mushroom spines have larger postsynaptic densities (PSDs) [1], which anchor more AMPA glutamate receptors and make these synapses functionally stronger [8–12].”
AMPA receptor trafficking at excitatory synapses. (2003, neutral): “(Matsuzaki et al., 2001).”