Diversity of the Human Intestinal Microbial Flora

By P. Eckburg, E. Bik, C. Bernstein, Elizabeth Purdom, Les Dethlefsen, Michael Sargent, S. Gill, K. Nelson, David A. Relman. Science, 2005

7,909 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/0390499c1cac3007ab822414011c81c06529bde1

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Citations in the corpus

Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease (2012, background): “Firmicutes and Bacteroidetes account for >90% of the bacterial population in the colon [4] while Actinobacteria and Proteobacteria (which includes Enterobacteriaceae) are regularly present but are scarce (<1%–5%) [1].”
Folate Production by Probiotic Bacteria (2011, background): “Although more than 50 bacterial phyla have been described, it is dominated by Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria [7].”
The influence of sex, handedness, and washing on the diversity of hand surface bacteria (2008, background): “The bacterial communities found on the skin surface, like those communities found in other human-associated microbial habitats (2, 15, 20, 21), exhibit an enormous amount of interindividual variability.”
The gut microbiota and inflammatory bowel disease (2014, unknown): “For example, the composition of the microbiota is significantly different between fecal and mucosal samples [5, 21].”
Fecal source tracking, the indicator paradigm, and managing water quality. (2007, background): “‘‘Uncultivated’’ bacteria can provide host-specific molecular markers, and are more common in feces than cultivated ones (Eckburg et al., 2005).”
Meta-analyses of human gut microbes associated with obesity and IBD (2014, background): “Epithelial-associated microbes of the small and large intestine are different than fecal microbiota [35,36], and are more likely to be key players in the etiology of IBD because of their more direct interaction with the affected tissues and the mucosal immune system.”
Diversity of the human gastrointestinal tract microbiota revisited. (2007, methodology): “…(SSU) (16S and 18S) ribosomal RNA (rRNA)-based, and traditional cultivation studies show that the mere selection of some different subjects is sufficient for the discovery of novel intestinal inhabitants (Holmstrom et al., 2004; Eckburg et al., 2005; Kitahara et al., 2005; Wang et al., 2005).”
Short-Term Antibiotic Treatment Has Differing Long-Term Impacts on the Human Throat and Gut Microbiome (2010, methodology): “284 The antibiotic treatment impacted the indigenous microbiota differently in the 285 individual treated subjects, probably due to the known unique bacterial community 286 compositions in different individuals [1,23,30,31,32].”
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. (2007, background): “The intestinal bacterial community is composed of at least 500 different bacterial species, most of which are as yet unculturable ( Eckburg et al., 2005 ).”