A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.

By A. Mckie, P. Marciani, A. Rolfs, K. Brennan, Kristina Wehr, D. Barrow, S. Miret, A. Bomford, T. Peters, F. Farzaneh and 3 more. Molecules and Cells, 2000

1,454 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/037d8812045d5947f51419496cbc243ebd163a93

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. T. Ganz
2. Kostas Pantopoulos
3. C. Wood
4. C. Brauner
5. A. Farrell
6. D. Richardson
7. D. Kalinowski
8. G. Papanikolaou

In Hematology

1. T. Ganz
2. Kostas Pantopoulos
3. G. Papanikolaou
4. C. Wood
5. C. Brauner
6. A. Farrell
7. D. Richardson
8. D. Kalinowski

In Nutrition and Dietetics

1. T. Ganz
2. C. Wood
3. C. Brauner
4. A. Farrell
5. K. Waldron
6. G. Papanikolaou
7. Kostas Pantopoulos
8. D. Templeton

Citations in the corpus

• Systemic iron homeostasis. (2013, background): “In the mouse, duodenal ferroportin mRNA is increased by hypoxia and iron deficiency (39, 147, 151, 274), and hypoxia and anemia increase ferroportin mRNA in macrophages but not hepatocytes (39).”
• Iron metabolism and toxicity. (2005, background): “, 2000), also found in literature as IREG1 (McKie et al., 2000) or MTP1 (Abboud and Haile, 2000), which is thought to function in concert with the membrane ferroxidase hephaestin.”
• Metalloproteins and metal sensing (2009, background): “Ferroportin is otherwise responsible for iron export into the circulation across the basolateral membrane of enterocyte”
• The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer (2005, background): “Several proteins have been implicated in the trafficking and release of iron, including hephaestin (Vulpe et al., 1999) and ferroportin 1 (also known as metal transporter 1 or iron-regulated transporter 1; Abboud and Haile, 2000; Donovan et al., 2000; McKie et al., 2000).”
• Molecular and Cellular Iron Transport (2002, background): “Recently, it has also been used as a scaffold to engineer a peptide into a surface-exposed loop (48,49).”
• Iron in Infection and Immunity (2013, background): “N IH -PA Author M anuscript N IH -PA Author M anuscript (Abboud and Haile, 2000; Donovan et al., 2000; McKie et al., 2000).”
• In vivo analysis of metal distribution and expression of metal transporters in rice seed during germination process by microarray and X-ray Fluorescence Imaging of Fe, Zn, Mn, and Cu (2009, background): “…ATPase family (Mills et al. 2003), the oligopeptide transporter (OPT) superfamily (Curie et al. 2001), the iron-regulated protein (IREG) family (McKie et al. 2000; Schaaf et al. 2006), IDI7, an Fe deficiency-induced ABC transporter identified in barley (Yamagichi et al. 2002), PIC1, an Fe…”