Description of Parkinson's Disease as a Clinical Syndrome
By S. Fahn. Annals of the New York Academy of Sciences, 2003
993 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Neurology
View Paper: https://www.semanticscholar.org/paper/01ad0d8c1c100cfdb1c1f51d8569a0f2338092f0
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In Cellular and Molecular Neuroscience
In Neurology
- V. Lee
- John Q. Trojanowski
- Kelvin C. Luk
- Bin Zhang
- M. Farrer
- Dennis W. Dickson
- T. Dawson
- Valina L. Dawson
Citations in the corpus
- Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice (2012, neutral): “1K,L) that project to medium spiny neurons of the dorsal striatum and whose selective degeneration is a major contributor to motor deficits in PD (24).”
- Genetics of Parkinson disease: paradigm shifts and future prospects (2006, background): “Disease prevalence is age-associated, with approximately 1% of the population being affected at 65 years, increasing to 4–5% in 85-year-old”
- Parkinson's disease: genetics and pathogenesis. (2011, background): “PD is typically a chronic and slowly progressive disorder with a mean duration of 15 years from disease recognition until death, although affected individuals can frequently survive two decades or longer (6, 7).”
- Neuroinflammation in Parkinson’s disease and its potential as therapeutic target (2015, background): “Introduction Parkinson’s disease (PD) is an age-related neurodegenerative disorder characterized clinically by resting tremor, slowness of movement, rigidity and postural instability and pathologically by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) ”
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice (2012, background): “Importantly, the pro gression of Syn pathology in PD appears to follow a stereotypical pattern that com mences in the brainstem and extends rostrally to neocortical regions (Braak et al., 2003; Fahn, 2003).”