PUMA, a novel proapoptotic gene, is induced by p53.

By K. Nakano, Karen H. Vousden. Molecules and Cells, 2001

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis (2003, background): “The presence of several BH3-only proteins, such as tBid, Bim, Noxa, and Puma, at mitochondria when apoptosis is triggered has suggested that the activation of Bax/Bak by BH3-only proteins may take place at this site (Li et al., 1998; Luo et al., 1998; Puthalakath et al., 1999; Oda et al., 2000; Naka”
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario (2006, background): “Other BH3-only proteins such as BAD are activated by dephosphorylation, whereas PUMA and Noxa are transcriptionally upregulated by p53 and other proapoptotic stimuli.(23,24) In the presence of antiapoptotic BCL-2 proteins, activation of a direct activator BH3-only protein is generally not considered”
Anoikis: an emerging hallmark in health and diseases (2012, background): “For example, Noxa and Puma are transcriptionally regulated by p53 and have been implicated in fibroblast anoikis [27,28].”
Role of p53 in Cell Death and Human Cancers (2011, background): “PUMA has been identified as one of p53-target gene products [86,87].”