Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription.

By Yongfeng Shang, Xiao Hu, J. Direnzo, Mitchell A. Lazar, Myles A. Brown. Cell, 2000

1,766 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/01358c778364ecc513dfe88aa959e13807d1be47

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In Genetics

1. Carolyn L. Smith
2. B. O’Malley
3. Jason S. Carroll
4. Fanxin Long
5. Myles A. Brown
6. Arul M. Chinnaiyan
7. X. S. Liu
8. J. Massagué

In Molecular Biology

1. J. Massagué
2. B. Spiegelman
3. J. Seoane
4. X. S. Liu
5. Clifford A. Meyer
6. Myles A. Brown
7. Jason S. Carroll
8. P. Puigserver

Citations in the corpus

• Androgen receptor (AR) coregulators: an overview. (2002, background): “After the initiation of transcription, ER , SRC-3, and PBP cease to be associated with the promoter, presumably to begin another cycle of reinitiation (139).”
• Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions (2006, neutral): “Coimmunoprecipitated DNA fragments captured by protein A–agarose beads were washed according to ref”
• Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer (2009, neutral): “ChIP and two-step ChIP were performed as described previously ( Shang et al., 2000 ).”
• Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage (2002, methodology): “Chromatin immunoprecipitations were performed essentially as previously describe”
• Transcriptional complexes engaged by apo‐estrogen receptor‐α isoforms have divergent outcomes (2004, background): “ERa induces the ordered recruitment of a series of coactivator complexes, leading to histone acetylation, methy- lation, chromatin remodeling and recruitment of the basal transcription machinery (Shang et al, 2000; Belandia and Parker, 2003; Métivier et al, 2003).”
• The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. (2003, background): “New RNAi approaches combining multiple somatic knockouts of transcription components in a single cell may soon shed new light on various aspects of NR and coregulator functions (235, 422).”
• Genome-wide analysis of estrogen receptor binding sites (2006, background): “Estrogen receptor–mediated transcription has been intensively studied on a small number of endogenous target promoter”
• LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. (2009, methodology): “In addition, sequential ChIP or ChIP/Re-ChIP (Shang et al., 2000; Zhang et al., 2004) confirmed that LSD1, MTA3, and Mi-2 exist in the same protein complex on the TGFB1 promoter (Figure 5C).”
• Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. (2004, background): “Biotechnology) as previously described ( 16 ), with minor modifications.”