LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.

By Yan Wang, Hua Zhang, Yupeng Chen, Yimin Sun, Fen Yang, Wenhua Yu, Jingrui Liang, Luyang Sun, Xiaohan Yang, Lei Shi and 6 more. Cell, 2009

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Enhancer decommissioning by LSD1 during embryonic stem cell differentiation (2012, positive): “To gain further insight into the role of LSD1 in ESC differentiation, we investigated whether LSD1 is associated with previously described complexes, including NuRD, cofactor of REST (CoREST), and the androgen receptor/oestrogen receptor complexe”
Epithelial-mesenchymal transitions in development and disease. (2009, background): “…metastasis by incorporating into the complex the metastasis tumor antigen MTA3 or the lysinespecific demethylase LSD1, that prevent EMT by repressing Snail expression or by an epigenetic mechanism that inversely correlates with TGFβ signaling, respectively (Fujita et al., 2003; Wang et al., 2009b).”
Covalent histone modifications: miswritten, misinterpreted, and miserased in human cancers (2010, background): “3a ), has been shown to inhibit metastasis in breast cance”