J. Chmielecki
Pulmonary and Respiratory Medicine · 2010–2017
A researcher in the Science corpus: 7 papers; trusts 4 researchers and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Pulmonary and Respiratory Medicine — 96 citations into it
- Oncology — 90 citations into it
Whom J. Chmielecki trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Papers from J. Chmielecki's perspective
Ordered by how strongly the researchers J. Chmielecki trusts endorse each paper. Same corpus, a different order for every researcher.
- Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification (Science)
- Novel D761Y and Common Secondary T790M Mutations in Epidermal Growth Factor Receptor–Mutant Lung Adenocarcinomas with Acquired Resistance to Kinase Inhibitors (Clinical Cancer Research)
- Mutations of the BRAF gene in human cancer (Nature)
- KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib (PLoS Medicine)
- Novel mutant-selective EGFR kinase inhibitors against EGFR T790M (Nature)
- RAF inhibitors transactivate RAF dimers and ERK signaling in cells with wild-type BRAF (Nature)
- Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer (Nature)
- ERBB Receptors and Cancer: The Complexity of Targeted Inhibitors (Nature Reviews. Cancer)
- Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants (PLoS Medicine)
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP (Proceedings of the National Academy of Sciences of the United States of America)
Their papers
- Comprehensive molecular profiling of lung adenocarcinoma (2014) — 5,176 citations
- Anchored multiplex PCR for targeted next-generation sequencing (2014) — 832 citations
- Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden (2017) — 3,045 citations
- Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. (2015) — 714 citations
- Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. (2014) — 649 citations
- Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation (2010) — 619 citations
- Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer (2010) — 1,084 citations