P. Jänne
Oncology · 2004–2022
A researcher in the Science corpus: 38 papers; trusts 6 researchers and is trusted by 7 researchers here, as inferred from the citation graph.
Subfields
- Oncology — 358 citations into it; #626 of 1,698 by trust here, #24 by citations
- Pulmonary and Respiratory Medicine — 304 citations into it; #109 of 770 by trust here, #3 by citations
- Molecular Biology — 185 citations into it
- Hematology — 65 citations into it
Whom P. Jänne trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts P. Jänne overall
Papers from P. Jänne's perspective
Ordered by how strongly the researchers P. Jänne trusts endorse each paper. Same corpus, a different order for every researcher.
- Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification (Science)
- EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy (Science)
- Novel D761Y and Common Secondary T790M Mutations in Epidermal Growth Factor Receptor–Mutant Lung Adenocarcinomas with Acquired Resistance to Kinase Inhibitors (Clinical Cancer Research)
- KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib (PLoS Medicine)
- EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. (New England Journal of Medicine)
- Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. (Cancer Research)
- Clinical Course of Patients with Non–Small Cell Lung Cancer and Epidermal Growth Factor Receptor Exon 19 and Exon 21 Mutations Treated with Gefitinib or Erlotinib (Clinical Cancer Research)
- Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain (PLoS Medicine)
- Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. (Cancer Cell)
- Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. (Journal of the National Cancer Institute)
Their papers
- Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing (2012) — 1,811 citations
- MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling (2007) — 4,374 citations
- EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. (2005) — 4,065 citations
- Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants (2005) — 677 citations
- Novel mutant-selective EGFR kinase inhibitors against EGFR T790M (2009) — 979 citations
- PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. (2007) — 708 citations
- A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors (2011) — 620 citations
- Kinase drug discovery 20 years after imatinib: progress and future directions (2021) — 812 citations
- Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study. (2013) — 670 citations
- Adagrasib in Non-Small-Cell Lung Cancer Harboring a KRASG12C Mutation. (2022) — 699 citations
- Trastuzumab Deruxtecan in HER2-Mutant Non–Small-Cell Lung Cancer (2021) — 749 citations
- STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma (2018) — 1,344 citations
- Assessment of Resistance Mechanisms and Clinical Implications in Patients With EGFR T790M-Positive Lung Cancer and Acquired Resistance to Osimertinib (2018) — 631 citations
- Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints (2016) — 1,425 citations
- Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity (2016) — 658 citations
- Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non-Small-Cell Lung Cancer. (2016) — 715 citations
- Overcoming EGFR T790M and C797S resistance with mutant-selective allosteric inhibitors (2016) — 757 citations
- MET Exon 14 Mutations in Non-Small-Cell Lung Cancer Are Associated With Advanced Age and Stage-Dependent MET Genomic Amplification and c-Met Overexpression. (2016) — 640 citations
- Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy (2015) — 344 citations
- Acquired EGFR C797S mediates resistance to AZD9291 in advanced non-small cell lung cancer harboring EGFR T790M (2015) — 1,104 citations