Smita S. Patel
Immunology · 2011–2018
A researcher in the Science corpus: 4 papers; trusts 1 researcher and is trusted by 2 researchers here, as inferred from the citation graph.
Subfields
- Immunology — 46 citations into it; #862 of 2,160 by trust here, #1,196 by citations
- Molecular Biology — 39 citations into it; #8,949 of 17,773 by trust here, #7,980 by citations
Whom Smita S. Patel trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts Smita S. Patel overall
Papers from Smita S. Patel's perspective
Ordered by how strongly the researchers Smita S. Patel trusts endorse each paper. Same corpus, a different order for every researcher.
- The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
- Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.
- Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
- Global rigid body modeling of macromolecular complexes against small-angle scattering data. (Biophysical Journal)
- Structural characterization of flexible proteins using small-angle X-ray scattering. (Journal of the American Chemical Society)
- Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2 (Proceedings of the National Academy of Sciences of the United States of America)
- Structural and functional insights into pattern recognition by the innate immune receptor RIG-I
- Recognition of 5′-triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative strand virus
- Small self-RNA generated by RNase L amplifies antiviral innate immunity (Nature)
- Structure and mechanism of helicases and nucleic acid translocases. (Annual Review of Biochemistry)
Their papers
- Structural Basis of RNA Recognition and Activation by Innate Immune Receptor RIG-I (2011) — 440 citations
- Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I (2016) — 313 citations
- RIG-I uses an ATPase-powered translocation-throttling mechanism for kinetic proofreading of RNAs and oligomerization (2018) — 66 citations
- HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity (2018) — 33 citations