David C. Wedge

Molecular Biology · 2012–2020

A researcher in the Science corpus: 20 papers; trusts 2 researchers and is trusted by 2 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 320 citations into it; #13,558 of 17,773 by trust here, #750 by citations
• Cancer Research — 268 citations into it; #1,135 of 1,780 by trust here, #58 by citations
• Oncology — 93 citations into it
• Pulmonary and Respiratory Medicine — 81 citations into it
• Artificial Intelligence — 14 citations into it
• Computer Vision and Pattern Recognition — 5 citations into it

Whom David C. Wedge trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Michael R. Stratton
2. Anil K. Jain

Who trusts David C. Wedge overall

1. Nicholas McGranahan
2. Charles Swanton
3. Ludmil B. Alexandrov

Papers from David C. Wedge's perspective

Ordered by how strongly the researchers David C. Wedge trusts endorse each paper. Same corpus, a different order for every researcher.

1. Learning the parts of objects by non-negative matrix factorization
2. The genomic complexity of primary human prostate cancer (Nature)
3. Discovery and saturation analysis of cancer genes across 21 tumor types (Nature)
4. Pan-cancer patterns of somatic copy-number alteration (Nature Genetics)
5. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. (New England Journal of Medicine)
6. Transcription-coupled DNA repair: two decades of progress and surprises (Nature reviews. Molecular cell biology)
7. Exploring the Genomes of Cancer Cells: Progress and Promise (Science)
8. Absolute quantification of somatic DNA alterations in human cancer (Nature Biotechnology)
9. A small cell lung cancer genome reports complex tobacco exposure signatures (Nature)
10. Metagenes and molecular pattern discovery using matrix factorization (Proceedings of the National Academy of Sciences of the United States of America)

Their papers

• Signatures of mutational processes in human cancer (2013) — 9,146 citations
• Mutational Processes Molding the Genomes of 21 Breast Cancers (2012) — 1,882 citations
• The landscape of cancer genes and mutational processes in breast cancer (2012) — 1,739 citations
• Clock-like mutational processes in human somatic cells (2015) — 981 citations
• The Life History of 21 Breast Cancers (2012) — 1,476 citations
• Deciphering Signatures of Mutational Processes Operative in Human Cancer (2013) — 1,186 citations
• Spatial and temporal diversity in genomic instability processes defines lung cancer evolution (2014) — 1,056 citations
• Genomic Evolution of Breast Cancer Metastasis and Relapse (2017) — 605 citations
• The evolutionary history of 2,658 cancers (2017) — 937 citations
• Heterogeneity of genomic evolution and mutational profiles in multiple myeloma (2014) — 862 citations
• Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor (2020) — 322 citations
• Landscape of somatic mutations in 560 breast cancer whole genome sequences (2016) — 2,045 citations
• Subclonal diversification of primary breast cancer revealed by multiregion sequencing (2015) — 764 citations
• The Evolutionary History of Lethal Metastatic Prostate Cancer (2015) — 1,348 citations
• High burden and pervasive positive selection of somatic mutations in normal human skin (2015) — 1,462 citations
• Intra-tumor Heterogeneity in Localized Lung Adenocarcinomas Delineated by Multi-region Sequencing (2014) — 884 citations
• Clinical and biological implications of driver mutations in myelodysplastic syndromes. (2013) — 1,780 citations
• A comparison of Raman and FT-IR spectroscopy for the prediction of meat spoilage (2013) — 134 citations
• Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2 (2013) — 1,750 citations
• Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone (2013) — 775 citations