Optimization of thermostable lipase production from a thermophilic Geobacillus sp. using Box-Behnken experimental design

By Y. Abdel-Fattah. Biotechnology Letters, 2002

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Applications of Response Surface Methodology in the Food Industry Processes (2017, methodology): “Statistical experimental approaches such as RSM are much better since they suggest simultaneous, systematic, and efficient variation of all the components for process optimization economically (Abdel-Fattah, 2002). As shown in Table 4, the highest EA of xylanase was measured at 61 U/mL from Chaetomi”
Bacterial lipases: an overview of production, purification and biochemical properties (2004, methodology): “Abdel-Fattah (2002) reported a 4-fold increase in lipase production in shake-flask cultures from a thermophilic Geobacillus sp., using a Box–Behnken experimental design.”
Molecular cloning and characterization of thermostable esterase and lipase from Geobacillus thermoleovorans YN isolated from desert soil in Egypt (2007, methodology): “The production of esterase/lipase was optimised in shake flask cultures using a Box-Behnken experimental design and led to a yield of 495 U/l [18].”