P[acman]: A BAC Transgenic Platform for Targeted Insertion of Large DNA Fragments in D. melanogaster
By K. Venken, Yuchun He, R. Hoskins, Hugo J. Bellen. Science, 2006
833 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/fe780600ad4e9f5f8a8bf0379191116246463894
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
- Julie H. Simpson
- Hugo J. Bellen
- K. Venken
- S. Zipursky
- C. Tsui
- Yi Chen
- Aljoscha Nern
- Matthew Y. Pecot
In Molecular Biology
- Julie H. Simpson
- Hugo J. Bellen
- K. Venken
- S. Zipursky
- C. Tsui
- Yi Chen
- Aljoscha Nern
- Matthew Y. Pecot
Citations in the corpus
- Generating Customized Transgene Landing Sites and Multi-Transgene Arrays in Drosophila Using phiC31 Integrase (2015, background): “The Drosophila community benefits from having several landing sites that have been extensively characterized (Venken et al. 2006; Bischof et al. 2007; Markstein et al. 2008; Pfeiffer et al. 2010), allowing researchers to select sites to maximize transgene expression and minimize the impact of…”
- Genetic manipulation of genes and cells in the nervous system of the fruit fly (2011, methodology): “Recombineering was first introduced into the Drosophila field as a versatile transgenic platform named P[acman] (P/FC31 artificial chromosome for manipulation) (Venken et al., 2006).”
- Refinement of Tools for Targeted Gene Expression in Drosophila (2010, neutral): “Genomic attP site references: attP1, attP2, attP3, attP18, and attP40 (Groth et al. 2004; Markstein et al. 2008); attP16 (Markstein et al. 2008); VK00005, VK00016, VK00026, and VK00027 (Venken et al. 2006); and su(Hw)attP1, su(Hw)attP2, su(Hw)attP4, su(Hw)attP5, su(Hw)attP6, and su(Hw)attP8 (Ni et a”
- Cell-type Specific Labeling of Synapses in vivo through Synaptic Tagging with Recombination (STaR) (2014, methodology): “While we used BAC recombineering techniques to modify genomic loci of synaptic proteins (Venken et al., 2006), a variety of additional methods are available to generate STaR-based markers, such as Minos-mediated integration cassette (MiMIC) insertions (Venken et al., 2011) and site-specific…”
- MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes (2011, methodology): “should allow the manipulation of most genes by engineering and integrating large genomic constructs using the P[acman] syste”