Sleep in Drosophila is regulated by adult mushroom bodies

By W. Joiner, A. Crocker, B. White, A. Sehgal. 2006

467 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Plant Science

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Yoshinori Aso
2. Gerald M. Rubin
3. Hiromu Tanimoto
4. S. Waddell
5. T. Préat
6. P. Plaçais
7. Kei Ito
8. N. Tanaka

In Genetics

1. Yoshinori Aso
2. Gerald M. Rubin
3. S. Waddell
4. Hiromu Tanimoto
5. T. Préat
6. P. Plaçais
7. Kei Ito
8. N. Tanaka

In Plant Science

1. Hiromu Tanimoto
2. P. Plaçais
3. J. Armstrong
4. T. Préat

Citations in the corpus

• Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “…play a role in experiencedependent regulation of proboscis extension (Masek and Scott, 2010) and courtship (McBride et al., 1999) as well as regulation of sleep (Joiner et al., 2006; Pitman et al., 2006) and post-mating behaviors such as oviposition (Fleischmann et al., 2001; Azanchi et al., 2013).”
• Short neuropeptide F is a sleep-promoting inhibitory modulator (2013, methodology): “We used multiple strategies to test the involvement of the MB because it is a previously identified sleep-promoting region (Joiner et al., 2006; Pitman et al., 2006) Addition of a MB-GAL80 transgene blocked the expression of dTRPA1 in the MB without affecting the sleep-promoting effect of sNPFGAL4:d”
• Molecular architecture of smell and taste in Drosophila. (2007, background): “The MBs are integrative centers controlling various functions such as olfactory learning, other forms of learning (Heisenberg 2003, Davis 2005), locomotor activity (Martin et al. 1998), male courtship behavior (Sakai & Kitamoto 2006), and sleep ( Joiner et al. 2006, Pitman et al. 2006).”
• A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster (2015, background): “While it has been shown previously that the Drosophila MB can promote sleep (Joiner et al., 2006; Pitman et al., 2006; Yi et al., 2013), a specific role for the α’/β’ lobes has not been reported.”
• Dopamine Signalling in Mushroom Bodies Regulates Temperature-Preference Behaviour in Drosophila (2011, background): “However, MB is involved in behaviours like sleep [22], decision making [23], and learinig [24].”
• A neural circuit mechanism integrating motivational state with memory expression in Drosophila (2009, background): “Given the apparent role of the MB as a locomotor regulator (Huber, 1967; Martin et al., 1998; Pitman et al., 2006; Joiner et al., 2006), MB-MP neurons may also generally promote exploratory behavior.”
• Propagation of homeostatic sleep signals by segregated synaptic microcircuits of the Drosophila mushroom body (2015, unknown): “This is in contrast to the previous suggestion of a role for a/b KCs in regulating sleep [3] and is perhaps explained by differences between the traditional GAL4 driver used there and the split-GAL4 drivers used here.”
• Neuronal assemblies of the Drosophila mushroom body (2008, background): “…and Strausfeld, 1999; Liu et al., 1999; McBride et al., 1999; Joiner and Griffith, 1999; Tang and Guo, 2001; Perez-Orive et al., 2002; Siwicki and Ladewski, 2003; Besson and Martin, 2005; Brembs and Wiener, 2006; Joiner et al., 2006; Pitman et al., 2006; Acevedo et al., 2007; Keleman et al., 2007).”
• A map of olfactory representation in the Drosophila mushroom body. (2007, unknown): “The whole MBs (gray) are segmented from DiD-stained brains and used as internal references for brain warping.”
• Are mushroom bodies cerebellum-like structures? (2011, background): “, 2007a), habit formation (Brembs, 2009), sleep (Joiner et al., 2006; Pitman et al., 2006), fixation behavior and attention (van Swinderen, 2005; Xi et al.”
• Cell Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression (2016, unknown): “It also may reflect the more diverse role the KCs have on behavior including courtship, appetitive memory and sleep (Aso et al., 2014b; Joiner et al., 2006; Keleman et al., 2012; Owald et al., 2015).”