Seizure-induced neurogenesis: are more new neurons good for an adult brain?

By J. Parent, D. Lowenstein. 2002

211 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

Adult neurogenesis in brain repair: cellular plasticity vs. cellular replacement (2014, background): “…been shown that neurogenesis can be upregulated in neurogenic niches in response to different brain insults including ischemia (Jin et al., 2001; Harry, 2008; Osman et al., 2011), seizures (Parent and Lowenstein, 2002; Smith et al., 2005) and traumatic brain injury (Dash et al., 2001; Harry, 2008).”
Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline (2007, background): “lated that new neurons generated in response to epileptic activity may contribute to the pathological consequences of SE rather than represent an attempt by the injured brain to replace lost cells (Parent, 2002; Parent and Lowenstein, 2002).”
Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli (2003, background): “Prox-1 is a transcription factor that is active in and highly selective for hippocampal granule cells (Pleasure et al., 2000).”
Neuronal Differentiation in the Adult Hippocampus Recapitulates Embryonic Development (2005, background): “This rate is increased by enriched environment, voluntary exercise, specific learning paradigms, and pathological conditions such as seizures or ischemia (van Praag et al., 2000; Parent and Lowenstein, 2002; Kokaia and Lindvall, 2003).”
Seizures Accelerate Functional Integration of Adult-Generated Granule Cells (2006, unknown): “Many models of experimentally induced epilepsy increase the proliferation of neural progenitors that generate newborn granule cells (Parent and Lowenstein, 2002).”