GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.
By S. Pirker, C. Schwarzer, A. Wieselthaler, W. Sieghart, G. Sperk. Neuroscience, 2000
1,387 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Neurology, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/fc18b468b4f023fd0791e8b93db278839951c20b
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In Cellular and Molecular Neuroscience
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Citations in the corpus
- Extrasynaptic GABAA receptors: Their function in the CNS and implications for disease (2012, background): “The subunit identity of the final assembly also determines the synaptic or extrasynaptic localization of GABAARs within a neuron (Pirker et al., 2000), reflecting the existence of various subunit assembly rules and anchoring/trafficking mechanisms (Luscher et al., 2011; Vithlani et al., 2011).”
- Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of γ‐aminobutyric acid type A receptor α1 subunit knockout mice (2006, background): “The 1 subunit is present in most nuclei, except for the reticular nucleus, which selectively contains 3-GABAA receptors (Fritschy and Mohler, 1995; Pirker et al., 2000).”
- Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy (2002, background): “Differences in the developmental features, or in the relative anatomical distribution of the γ2 and α1 subunits, might explain some of the differences observed in the clinical expression of the diseas”
- Distribution of α1, α4, γ2, and δ subunits of GABAA receptors in hippocampal granule cells (2004, methodology): “The antibodies against the g2 (1–33) and y (1–44) subunit of the GABAA receptor have been characterized extensively in the past by immunoprecipitation, Western blot, and immunohistochemistry [11,19– 22,32].”
- Neonatal development of the rat visual cortex: synaptic function of GABAa receptor α subunits (2002, methodology): “While bretazenil has been reported to elicit the greatest enhancement at a3containing receptors (Puia et al. 1992), this study did not take into account the lower GABA affinity of the a3bg2 receptor subtype relative to the other GABAA receptor subtypes used in these experiments.”
- GABAA receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain (2002, background): “A remarkably similar localization of these two subunits in wild-type mice was observed in the present study, and previous in situ hybridization and imunohistochemical studies have also shown similar distributions of these two subunits (Wisden et al., 1992; Pirker et al., 2000).”
- GABAA Receptors: Subtypes Provide Diversity of Function and Pharmacology (2008, neutral): “In situ hybridization (Wisden et al., 1992; Persohn et al., 1992) and immunohistochemical studies (Pirker et al., 2000; Fritschy et al., 1992) have indicated that a1, b1, b2, b3, and g2 subunits are found throughout the brain, although differences in their distribution were observed.”
- International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update (2008, background): “The 2 and 3 subunits are moderately abundant and 5 is relatively rare except in the hippocampus, as indicated by regional distribution and immunoprecipitation studies (Pirker et al., 2000; Sieghart and Sperk, 2002).”