Cadherins as modulators of cellular phenotype.

By M. Wheelock, Keith R. Johnson. Annual Review of Cell and Developmental Biology, 2003

707 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/fb09d26ea3220ed56ebb3b78d7e2eadb30f8d194

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. A. Cano
2. M. Maeda
3. Thomas Brabletz
4. S. Mitra
5. Daniel A. Hanson
6. Cornelis J. F. van Noorden
7. Simone Brabletz
8. M. Wheelock

In Molecular Biology

1. Thomas Brabletz
2. Simone Brabletz
3. G. Berx
4. A. Cano
5. O. Schmalhofer
6. R. Weinberg
7. M. Maeda
8. S. Mitra

Citations in the corpus

• The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity (2007, background): “Ectopic E-cadherin expression is not sufficient to induce epithelial genes Expression of E-cadherin in undifferentiated cancer cells rescues epithelial architecture and affects several signalling pathways (Wheelock and Johnson, 2003).”
• Biological Physics of the Developing Embryo (2005, neutral): “For example, it ignores the possible interaction between receptors on the same cell surface (cis interactions) or the role of the cytoskeleton in adhesion, factors that have been shown important for cadherin function (Wheelock and Johnson, 2003).”
• Cadherin switching (2008, background): “Cadherins are important in the establishment of cell polarity and cell sorting during embryonic development (reviewed in Gumbiner, 2005; Patel, S. et al., 2003; Wheelock and Johnson, 2003a; Wheelock and Johnson, 2003b).”
• Focal adhesion kinase: in command and control of cell motility (2005, background): “Cadherins are transmembrane proteins that mediate Ca 2+ -dependent homophilic protein–protein attachments between cells and that are also linked to the actin cytoskeleton through interaction with α- or β-catenin”
• Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, background): “Binding of tight junctional proteins to actinmicrofilaments and signaling proteins allows the transfer of signals into the cell (Bazzoni et al., 1999; Braga, 2002; Matter and Balda, 2003; Wheelock and Johnson, 2003).”
• DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells (2005, background): “The epithelial cell–cell adhesion protein E-cadherin is a potent suppressor of tumour cell invasion and metastasis (Cavallaro et al., 2002; Conacci-Sorrell et al., 2002; Wheelock and Johnson, 2003).”
• E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer (2009, background): “to play an important role in induction of EMT in development and tumorigenesis [17–19].”