The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.

By R. Veech. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2004

746 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics (2017, background): “In rodents, this KE decreases caloric intake and plasma total cholesterol, stimulates brown adipose tissue, and improves insulin resistance (Kashiwaya et al., 2010; Kemper et al., 2015; Veech, 2013).”
Cancer as a metabolic disease (2010, background): “Since the cytosolic free NADP/NADPH concentration couple is in near equilibrium with the glutathione couple, ketone body metabolism will also increase the reduced form of glutathione thus facilitating destruction of hydrogen peroxide [10,84,300].”
Mitochondrial Energetics and Therapeutics (2010, positive): “Since the 1920s, fasting and the ketogenic diet have been known to be one of the most effective approaches for treatment of intractable seizures in children (285).”