Inflammation and cancer: back to Virchow?

By F. Balkwill, A. Mantovani. The Lancet, 2001

7,715 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/fa43fe8312d0076efe2f68140cdf3a28526ccaa1

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In Oncology

Citations in the corpus

Role of chemokines in tumor growth. (2007, background): “Pro-inflammatory chemokines produced by the infiltrating leukocytes or the neoplastic tissues recruit Th2 cells and regulatory T cells (Treg) [1].”
Macrophages, innate immunity and cancer: balance, tolerance, and diversity. (2010, background): “Introduction After a long eclipse, in recent years different lines of work have lead to a renaissance of the inflammation–cancer connection [1–3].”
Inflammation: gearing the journey to cancer. (2008, background): “Like cytokines, chemokines also act by interacting with specific receptors expressed by both infiltrated leukocytes and tumor cells in an autocrine or a paracrine fashion [1,61].”
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. (2007, background): “Although it is likely that inflammation contributes to tumor progression through multiple and diverse mechanisms ( 1 , 32, 33), the causative events connecting inflammation with cancer are not well understood.”
Candidate mechanisms for chemotherapy-induced cognitive changes (2007, background): “Studies have supported the association between inflammation and an increased risk of developing several types of cancer, including bladder, cervical and ovaria”
Tumour-educated macrophages promote tumour progression and metastasis (2004, background): “These haematopoietic cells have pivotal roles in the progression and metastasis of tumour”
Macrophages in immunoregulation and therapeutics (2023, background): “Cancer promotion and advancement: Chronic inflammation may be linked to tumor beginning since it was shown that there were many inflammatory cells in tumor biopsy samples.(306,307) This is true for gastric and colon cancer.”
Phagocytosis: An Immunobiologic Process. (2016, background): “Tumor-associated macrophages (TAMs) can promote rather than recognize and destroy nascent and established malignant cells, as well as enhance metastasis (Balkwill and Mantovani, 2001; Germano et al., 2013; Pollard, 2009).”