Neurotrophins: roles in neuronal development and function.

By E. Huang, L. Reichardt. Annual Review of Neuroscience, 2001

4,401 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/fa3b7f641c922ac46d4cbf471b8cd534a866e4b6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. B. Lu
2. R. Duman
3. T. Rantamäki
4. Eero Castrén
5. Keri Martinowich
6. H. Schmidt
7. B. K. Pedersen
8. B. Hempstead

In Developmental Neuroscience

1. B. Lu
2. R. Duman
3. B. K. Pedersen
4. Eero Castrén
5. H. Schmidt
6. T. Rantamäki
7. Keri Martinowich
8. B. Hempstead

Citations in the corpus

• A Developmental Switch in the Response of DRG Neurons to ETS Transcription Factor Signaling (2005, background): “Whereas expression of the neurotrophin receptors TrkA, TrkB, and TrkC marks afferents of distinct sensory modalities in DRG of wild-type embryos (Figure 6A–6C) [4,29], TauEWS-Pea3/þ Isl1Cre/þ embryos showed complete absence of expression of TrkA, TrkB, and TrkC in DRG neurons at E16.”
• Brain-derived neurotrophic factor and its clinical implications (2015, background): “Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors that support differentiation [1], maturation [2], and survival of neurons in the nervous system [3] and shows a neuroprotective effect under adverse conditions, such as glutamatergic stimulation, cerebral ischemia, hypoglyce”
• Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. (2003, background): “After binding and activating a specific receptor, that is, receptor tyrosine kinase B (trk B), BDNF is directly involved in neurite outgrowth, phenotypic maturation, morphological plasticity, and synthesis of proteins for differentiated functioning of neurons and synaptic functioning.(16) Results of”
• Brain-derived neurotrophic factor. (2004, background): “Certain peripheral sensory neurons, especially those in vestibular and nodosepetrosal ganglia, depend on the presence of BDNF because BDNF homozygous (2 /2 ) knockout mice lack these neurons (Huang and Reichardt, 2001).”
• Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. (2012, background): “In cultured cortical neurons, we found that dexamethasone (DEX, a selective GR agonist) inhibits BDNF-induced release of glutamate by decreasing GR–TrkB interaction and the PLC-γ pathway (Numakawa et al., 2009).”
• Role of neurotrophic factors in depression. (2007, background): “Introduction Neurotrophic factors are critical regulators of the formation and plasticity of neuronal networks [1].”
• Interaction between BDNF and Serotonin: Role in Mood Disorders (2008, background): “…survival of peripheral neurons, BDNF is now recognized as a plethoric factor able to regulate a wide repertoire of functions, including neuronal survival, migration, phenotypic differentiation, axonal and dendritic growth, and synapse formation (Huang and Reichardt, 2001; Lewin and Barde, 1996).”