Mechanism and role of PDZ domains in signaling complex assembly.

By Baruch Z. Harris, Wendell A. Lim. Journal of Cell Science, 2001

882 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f9b03bf8a4f655e40e265cceec7986267d696eb7

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Citations in the corpus

Graphical models of residue coupling in protein families (2005, background): “PDZ domains are protein-protein interaction domains that occur in many proteins and are involved in a wide variety of biological processes [10].”
Graphical models of protein–protein interaction specificity from correlated mutations and interaction data (2009, background): “34,35 Figure 3 shows a representative three dimensional structure of a PDZ domain interacting with a ligand.”
A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions (2012, background): “Furthermore, canonical PDZ domains are extremely rare in nonmetazoans (Harris and Lim, 2001), and are therefore unlikely to interact with endogenous yeast machinery.”
Graphical Models of Residue Coupling in Protein Families (2008, background): “PDZ domains are proteinprotein interaction domains that occur in many proteins and are involved in a wide variety of biological processes [ 10 ].”
Mechanisms of caspase activation and inhibition during apoptosis. (2002, background): “Since PDZ domains typically interact with the C-terminal During apoptosis, caspase-9 can be further cleaved after Asp330 by downstream caspases such as cas-hydrophobic residues of membrane receptors and ion channels (Harris and Lim, 2001), the PDZ domain in pase-3 (Figure 6).”
The role of the Rho GTPases in neuronal development. (2005, background): “2003), protein complex stabilization at the membrane by scaffolding molecules (Harris and Lim 2001), and protein targeting along the secretory or endosomal pathways (Jacob and Naim 2001; Keller et al.”
The vertebrate muscle Z-disc: sarcomere anchor for structure and signalling (2009, background): “PDZ domains are structural domains of 80–90 amino acids arranged in 5–6 b-strands and 2 a-helices and are involved in protein– protein interactions (Harris and Lim 2001).”
Molecular Structure and Physiological Functions of GABAB Receptors (2004, background): “Tamalin comprises multiple protein-interacting domains, including a 95-kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain (131), a leucinezipper region and a COOH-terminal PDZ-binding motif.”