TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma.

By J. Anido, A. Sáez-Borderías, Alba Gonzàlez-Juncà, L. Rodón, Gerard Folch, M. Carmona, Rosa M Prieto-Sánchez, I. Barba, E. Martínez-Sáez, L. Prudkin and 11 more. Cancer Cell, 2010

619 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/e51bf47e43aeb6f4b612bfe6d8fe0faa54a14f1b

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In Molecular Biology

1. Chuan He
2. Hailing Shi
3. V. Plaks
4. Zhike Lu
5. Zena Werb
6. M. Nieto
7. Jeremy N. Rich
8. Niwen Kong

In Oncology

1. V. Plaks
2. J. Lathia
3. M. Nieto
4. Zena Werb
5. Jeremy N. Rich
6. Niwen Kong
7. R. Weinberg
8. Pengfei Lu

Citations in the corpus

• Cancer stem cells in glioblastoma (2015, background): “A distinct subset of TGF-β-dependent CSCs expresses CD44 and ID1 (Anido et al. 2010), which are markers of functionally distinct CSCs.”
• m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells (2017, background): “Accordingly, the expression of CD44, a GSC marker (Anido et al., 2010; Pietras et al., 2014), was upregulated in METTL3 KD GSCs (Figure S1).”
• The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? (2015, positive): “Activation of TGF-b as well as WNT signaling pathways by hypoxia induces stemness by promoting an undifferentiated state in tumor cells (Anido et al., 2010; Scheel et al., 2011).”
• The ins and outs of the epithelial to mesenchymal transition in health and disease. (2011, background): “The opportunity to use patient-derived specimens opens the possibility of assessing the efficacy of different therapies in vitro, which would be helpful in predicting responses and in designing more personalized strategies (Anido et al. 2010).”