Subjective Memory Complaints and Cognitive Impairment in Older People

By Louise M. Reid, A. MacLullich. Dementia and Geriatric Cognitive Disorders, 2006

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How researchers see this paper

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A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease (2014, neutral): “Results of current studies on subjective cognitive decline (SCD) in preclinical AD are highly variable and a conclusive picture with regard to rate of decline, risk for conversion to AD dementia, role of biomarkers in disease course prediction, and other crucial questions is missing [36–38].”
Cognitive dysfunction in HIV patients despite long-standing suppression of viremia (2009, background): “Population-based studies conducted in HIVnegative healthy individuals have shown that the complaint of memory loss is frequent (20–70% according to studies) [11] but only rarely associated with current objective cognitive impairment [12,13].”
Rate of progression of mild cognitive impairment to dementia – meta‐analysis of 41 robust inception cohort studies (2009, background): “It is to be expected that when omitting SMC, people with baseline cognitive deficits progress more slowly as SMC are a known risk factor for dementia (83).”
Effects of memory training on cortical thickness in the elderly (2010, background): “…functions inextricably coupled to everyday function, is associated with increasing concern among the aging population (Anderson and McConnell, 2007; National Council on the Aging, 2000), and memory complaints are reported by up to 50% of adults aged 64 and over (Reid and MacLullich, 2006).”