A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease
By F. Jessen, R. Amariglio, M. Boxtel, Monique M. B. Breteler, M. Ceccaldi, Gaël Chételat, Bruno Dubois, C. Dufouil, K. Ellis, W. Flier and 26 more. Alzheimer's & Dementia, 2014
2,688 citations recorded by the source corpus.
There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD‐I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre‐mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD plus.
Subfields: Cognitive Neuroscience, Physiology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/7495dc44eef8e680c87003ea36a3fe57e017b795
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In Cognitive Neuroscience
- Philip Scheltens
- C. Duyckaerts
- Bruno Dubois
- Harald Hampel
- Habib Benali
- Reisa A. Sperling
- Clifford R. Jack Jr.
- Olaf Sporns
In Physiology
- Kaj Blennow
- Reisa A. Sperling
- Harald Hampel
- Clifford R. Jack Jr.
- P. Aisen
- Philip Scheltens
- Marie Odile Habert
- C. Duyckaerts
In Psychiatry and Mental health
- Kaj Blennow
- Reisa A. Sperling
- Harald Hampel
- Clifford R. Jack Jr.
- P. Aisen
- Philip Scheltens
- C. Duyckaerts
- Bruno Dubois
Citations in the corpus
- Preclinical Alzheimer’s disease: Definition, natural history, and diagnostic criteria (2016, background): “Subjective cognitive complaints and the more recent concept of subjective cognitive decline (SCD) have been proposed as potential indicators of a preclinical state of AD [212] because they may increase the risk of progressing to clinical AD.”
- The characterisation of subjective cognitive decline. (2020, methodology): “To identify the potential causes of SCD in an individual, we propose that the concern of cognitive decline is evaluated by obtaining the following information from them: (1) which cognitive domains are affected (eg, memory, language, executive functioning, visual–spatial abilities, orientation, and ”