Inflammatory Mediators and Modulation of Blood–Brain Barrier Permeability

By N. Abbott. Cellular and molecular neurobiology, 2000

789 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f665c970631c52f3cd154a45fa6c52abfb8b76e1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

In Oncology

Citations in the corpus

Annexin 1: a new paracrine agent secreted by a novel mechanism (2002, neutral): “2); modulation by bradykinin appears to involve B2 receptors, elevation of [Ca]i and activation of phospholipase A2 (Abbott, 2000).”
Hyperglycemic Crises in Adult Patients With Diabetes (2009, background): “A number of mechanisms have been proposed, which include the role of cerebral ischemia/hypoxia, the generation of various inflammatory mediators (72), increased cerebral blood flow, disruption of cell membrane ion transport, and a rapid shift in extracellular and intracellular fluids resulting in ch”
Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions (2006, background): “Intracellular Ca2+ is also central to the regulation of TJ integrity (Abbott 2000).”
Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options (2020, background): “, TNF, to BBB permeability changes via endothelial cell transcytosis by enhanced vesicular transport (Abbott, 2000).”
Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology (2005, background): “Histamine, a mediator of brain edema (Joó, 1993), has a dual action on brain endothelial cells (Abbott, 2000).”
Astrocytes and Brain Injury (2003, background): “After ischemia, vasogenic edema and blood–brain barrier disruption may occur by several mechanisms, including active solute transport, vesicular transport, opening of paracellular channels, and physical disruption of astrocyte–endothelial junctions (Westergaard et al., 1976; Petito, 1979; Abbott, 20”
The blood-brain barrier in systemic inflammation. (2017, positive): “…tight junction expression during peripheral inflammatory pain (Huber et al., 2002) Inflammatory mediators Effect demonstrated with (reviewed in Abbott, 2000): Bradykinin Serotonin Histamine Arachidonic acid Nitric oxide Cytokines Effect demonstrated with: TNF-a (Tsao et al., 2001) IL-1b (de…”
Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures (2005, background): “…al. 1991; Meyer et al. 1993; Dallinger et al. 2000; Polak et al. 2001), arachidonic acid metabolites (Nielsen & Nyborg, 1989, 1990; Hoste & Andries, 1991; Yu et al. 2001) and others (Benedito et al. 1991; Ferrari-Dileo et al. 1991; Ma et al. 1996; Krejcy et al. 1997; Abbott, 2000; Yu et al. 2003).”